Gene Symbol | AASS |
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Entrez Gene | 10157 |
Alt Symbol | LKR/SDH, LKRSDH, LORSDH |
Species | Human |
Gene Type | protein-coding |
Description | aminoadipate-semialdehyde synthase |
Other Description | alpha-aminoadipate semialdehyde synthase|alpha-aminoadipic semialdehyde synthase, mitochondrial|aminoadipic semialdehyde synthase|lysine-2-oxoglutarate reductase|lysine-ketoglutarate reductase /saccharopine dehydrogenase |
Swissprots | O95462 Q9UDR5 |
Accessions | AAF03526 EAL24343 EAW83564 EAW83565 Q9UDR5 AF229180 AAF44328 AJ007714 CAA07619 AK023446 BAG51195 AK225898 AK294326 BAG57598 BC144246 BC144247 BC156456 AAI56457 BC172503 AAI72503 BM669241 DA995180 XM_011515725 XP_011514027 XM_011515726 XP_011514028 XR_242220 XR_242221 XR_927326 NM_005763 NP_005754 |
Function | Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively. |
Subcellular Location | Mitochondrion {ECO:0000250}. |
Tissue Specificity | Expressed in all 16 tissues examined with highest expression in the liver. |
Top Pathways | Lysine degradation |
AASS / LKR / SDH Antibody Blocking Peptide - LS-E737 from LifeSpan Bioscience
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AASS / LKR / SDH Antibody Blocking Peptide - LS-E7091 from LifeSpan Bioscience
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AASS / LKR / SDH Antibody Blocking Peptide - LS-E23136 from LifeSpan Bioscience
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AASS-Antibody-C-term-Blocking-peptide - BP11094b from Abgent, a WuXi AppTec company
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AASS-Antibody-Center-Blocking-Peptide - BP2779c from Abgent, a WuXi AppTec company
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AASS peptide - orb218322 from Biorbyt
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AASS Blocking Peptide - abx063653 from Abbexa
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AASS Blocking Peptide - CBP2459 from Cohesion Biosciences
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Recombinant Human Alpha-aminoadipic semialdehyde synthase, mitochondrial(AASS) ,partial - CSB-YP883373HU CSB-EP883373HU CSB-BP883373HU CSB-MP883373HU from Cusabio
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Alpha-aminoadipic semialdehyde synthase, mitochondrial(AASS) ,partial - MBS1406490 from MyBioSource
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Recombinant Aminoadipate Semialdehyde Synthase (AASS) - RPC855Hu01 from Cloud-clone
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Recombinant Aminoadipate Semialdehyde Synthase (AASS) - RPC855Hu01 from Uscn Life Science Inc.
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Recombinant Aminoadipate Semialdehyde Synthase (AASS) - RPC855Mu01 from Uscn Life Science Inc.
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AASS Recombinant Protein Antigen - NBP1-82833PEP from Novus Biologicals
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AASS Recombinant Protein Antigen - NBP1-82832PEP from Novus Biologicals
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AASS Protein - NBP1-82831PEP from Novus Biologicals
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AASS Peptide, Human - M34GP00024H from Creative Peptides
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AASS Recombinant Protein (OPCD00994) - OPCD00994 from Aviva Systems Biology
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