AASS

Gene Symbol AASS
Entrez Gene 10157
Alt Symbol LKR/SDH, LKRSDH, LORSDH
Species Human
Gene Type protein-coding
Description aminoadipate-semialdehyde synthase
Other Description alpha-aminoadipate semialdehyde synthase|alpha-aminoadipic semialdehyde synthase, mitochondrial|aminoadipic semialdehyde synthase|lysine-2-oxoglutarate reductase|lysine-ketoglutarate reductase /saccharopine dehydrogenase
Swissprots O95462 Q9UDR5
Accessions AAF03526 EAL24343 EAW83564 EAW83565 Q9UDR5 AF229180 AAF44328 AJ007714 CAA07619 AK023446 BAG51195 AK225898 AK294326 BAG57598 BC144246 BC144247 BC156456 AAI56457 BC172503 AAI72503 BM669241 DA995180 XM_011515725 XP_011514027 XM_011515726 XP_011514028 XR_242220 XR_242221 XR_927326 NM_005763 NP_005754
Function Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively.
Subcellular Location Mitochondrion {ECO:0000250}.
Tissue Specificity Expressed in all 16 tissues examined with highest expression in the liver.
Top Pathways Lysine degradation

AASS CRISPR/Cas9 KO Plasmid (h) - sc-406408 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AASS HDR Plasmid (h) - sc-406408-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AASS Double Nickase Plasmid (h) - sc-406408-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AASS Double Nickase Plasmid (h2) - sc-406408-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AASS CRISPR Activation Plasmid (h) - sc-406408-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AASS CRISPR Activation Plasmid (h2) - sc-406408-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AASS Lentiviral Activation Particles (h) - sc-406408-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AASS Lentiviral Activation Particles (h2) - sc-406408-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AASS siRNA (h) - sc-89857 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AASS shRNA Plasmid (h) - sc-89857-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AASS shRNA (h) Lentiviral Particles - sc-89857-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU067561 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2616 from Sigma-Aldrich

Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2616 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

AASS siRNA (Human) - CRH6856 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AASS - MBS8234763 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Aass (NM_005763.3) - SHH228706 from Creative biogene

Category siRNA
Species Reactivities Human

Human AASS siRNA - orb267358 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AASS shRNA Plasmid (Human) - CHH6856 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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