ELOVL2

Gene Symbol ELOVL2
Entrez Gene 54898
Alt Symbol SSC2
Species Human
Gene Type protein-coding
Description ELOVL fatty acid elongase 2
Other Description 3-keto acyl-CoA synthase ELOVL2|ELOVL FA elongase 2|elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2|elongation of very long chain fatty acids protein 2|very-long-chain 3-oxoacyl-CoA synthase 2
Swissprots Q6P9E1 Q86W94 Q9NXB9
Accessions EAW55290 EAW55291 EAW55292 Q9NXB9 AJ420504 AK000341 BAA91096 AL080199 BC050278 AAH50278 BC060809 AAH60809 HQ448547 ADQ33026 XM_011514716 XP_011513018 XM_011514717 XP_011513019 NM_017770 NP_060240
Function Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n- 6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. {ECO:0000269|PubMed:12371743, ECO:0000269|PubMed:20937905}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:20937905}; Multi-pass membrane protein {ECO:0000255}.
Tissue Specificity Liver and testis. {ECO:0000269|PubMed:20937905}.
Top Pathways Fatty acid elongation, Biosynthesis of unsaturated fatty acids, Fatty acid metabolism

ELOVL2 (S-16) - sc-54874 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ELOVL2 (S-16): sc-54874. Western blot analysis of ELOVL2 expression in 3T3-L1 (A), Hep G2 (B), HeLa (C) and Y79 (D) whole cell lysates and mouse liver tissue extract (E).

ELOVL2 (K-14) - sc-54872 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ELOVL2 (K-14): sc-54872. Western blot analysis of ELOVL2 expression in 3T3-L1 whole cell lysate.

ELOVL2 (H-57) - sc-135059 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-ELOVL2 antibody - ab111162 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab111162 at 1/50 dilution staining ELOVL2 in paraffin-embedded Human testis tissue by Immunohistochemistry. The image on the right is treated with synthesized peptide.

Anti-ELOVL2 antibody [EPR11880] - ab176327 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11880
Western blot analysis on immunoprecipitation pellet from mouse liver lysate labeling ELOVL2 using ab176327 at a 1/10 dilution.

Anti-ELOVL2 antibody - N-terminal - ab95295 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ELOVL2 antibody - N-terminal (ab95295) at 1/100 dilution (TTBS (Tween-Tris Buffered Saline: 0.1% Tween-20 in 100 mM Tris-CL [pH 7.5], 0.9% NaCl)/1% NFDM (nonfat dried milk)) + HepG2 cell lysate at 35 µg with NFDM freshly made in TTBS at 10 %SecondaryEnzyme-linked secondary antibody (typically horseradish peroxidase or alkaline phosphatase) in TTBS/1% NFDM for 30 min. at room temperature

Anti-ELOVL2 Antibody (aa1-27, AP) - LS-C234917 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELOVL2 Antibody (aa1-27, FITC) - LS-C234921 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELOVL2 Antibody (aa1-27, Biotin) - LS-C234919 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELOVL2 Antibody (aa1-27, PE) - LS-C246881 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELOVL2 Antibody (aa1-27, Azide-free, HRP) - LS-C249901 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELOVL2 Antibody (aa1-27, APC) - LS-C234918 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELOVL2 Antibody (aa250-296) - LS-C291336 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ELOVL2 Antibody (aa7-36) - LS-C321098 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELOVL2 Antibody (aa1-27) - LS-C167736 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human testis tissue reacted with ELOVL2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

ELOVL2 Antibody - NBP2-33963 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: ELOVL2 Antibody [NBP2-33963] - Immunohistochemical staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.

ELOVL2 Polyclonal Antibody - bs-7053R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Paraformaldehyde-fixed, paraffin embedded mouse brain; Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (normal goat serum) at 37°C for 20min; Antibody incubation with ELOVL2 Polyclonal Antibody (bs-7053R) at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining.

ANTI-ELOVL2 (N-TERM) antibody produced in rabbit - SAB1303025 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>ELOVL2 (N-term): <B>Cat. No. SAB1303025</B>: ELOVL2 in Human testis tissue with ELOVL2 antibody (N-term) at 5 μg/mL.

Anti-ELOVL2 antibody produced in rabbit - HPA031877 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ELOVL2: <B>Cat. No. HPA031877</B>: Immunohistochemical staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.

ELOVL2-Antibody-N-term - AP9191a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of ELOVL2 Antibody (N-term) (Cat. #AP9191a) in HepG2 cell line lysates (35ug/lane). ELOVL2 (arrow) was detected using the purified Pab.

ELOVL2 Antibody - N-terminal region (OAAB05782) - OAAB05782 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

ELOVL2 antibody - GTX87054 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

ELOVL2 antibody, N-term - GTX80506 from GeneTex

Prices $319.00
Sizes 400 μl
Host Rabbit
Clonality Polyclonal
Anti-ELOVL2 antibody, N-term used in Flow cytometry/FACS. GTX80506

ELOVL2 Antibody (OAAF03636) - OAAF03636 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

ELOVL2 antibody - 70R-35430 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Search more