ELOVL2

Gene Symbol	ELOVL2
Entrez Gene	54898
Alt Symbol	SSC2
Species	Human
Gene Type	protein-coding
Description	ELOVL fatty acid elongase 2
Other Description	3-keto acyl-CoA synthase ELOVL2|ELOVL FA elongase 2|elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2|elongation of very long chain fatty acids protein 2|very-long-chain 3-oxoacyl-CoA synthase 2
Swissprots	Q6P9E1 Q86W94 Q9NXB9
Accessions	EAW55290 EAW55291 EAW55292 Q9NXB9 AJ420504 AK000341 BAA91096 AL080199 BC050278 AAH50278 BC060809 AAH60809 HQ448547 ADQ33026 XM_011514716 XP_011513018 XM_011514717 XP_011513019 NM_017770 NP_060240
Function	Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n- 6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. {ECO:0000269|PubMed:12371743, ECO:0000269|PubMed:20937905}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:20937905}; Multi-pass membrane protein {ECO:0000255}.
Tissue Specificity	Liver and testis. {ECO:0000269|PubMed:20937905}.
Top Pathways	Fatty acid elongation, Biosynthesis of unsaturated fatty acids, Fatty acid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ELOVL2 full length protein - ab162883 from Abcam Category Protein Source Wheat germ Species Human

ELOVL2 Antibody Blocking Peptide - LS-E9996 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ELOVL2 Protein - H00054898-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ELOVL2-Antibody-C-term-Blocking-peptide - BP13461b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ELOVL2-Antibody-N-term-Blocking-Peptide - BP9191a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ELOVL2 - H00054898-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ELOVL2 - H00054898-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ELOVL2 fusion protein - ag14143 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ELOVL2 fusion protein - ag14456 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

ELOVL2 Protein - NBP2-33287PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

ELOVL2 Peptide, Human - M34GP04876H from Creative Peptides Category Peptide Source Synthetic. Species Human

Elongation of very long chain fatty acids protein 2 (ELOVL2), Recombinant Protein - MBS7014208 from MyBioSource Category Protein Prices $1,110.00, $2,095.00, $3,300.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

Search more