TNIP3

Gene Symbol TNIP3
Entrez Gene 79931
Alt Symbol ABIN-3, LIND
Species Human
Gene Type protein-coding
Description TNFAIP3 interacting protein 3
Other Description A20-binding inhibitor of NF-kappa-B activation 3|ABIN-3 beta|Listeria induced|TNFAIP3-interacting protein 3|TNFAIP3-interacting protein 3 beta|TNIP3 beta|listeria-induced gene protein
Swissprots B4DVF5 B4E023 Q96PQ3 A1A574 Q96KP6 Q9H780 A8K2Z4
Accessions EAX05263 EAX05264 EAX05265 Q96KP6 AF277289 AAL02151 AJ320534 CAC85929 AK024815 BAB15018 AK290409 BAF83098 AK301058 BAG62667 AK303192 BAG64285 BC128408 AAI28409 BP335455 CD367219 DC389224 EF585496 ABQ40006 XM_011532256 XP_011530558 XM_011532257 XP_011530559 XM_011532258 XP_011530560 XM_011532259 XP_011530561 NM_001128843 NP_001122315 NM_001244764 NP_001231693 NM_024873 NP_079149
Function Binds to zinc finger protein TNFAIP3 and inhibits NF- kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13- acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding. {ECO:0000269|PubMed:17088249}.
Tissue Specificity Highly expressed in lung, lymph node, thymus and fetal liver. Expressed at lower levels in bone marrow, brain, kidney, spleen, leukocytes and tonsils. Could be detected in heart, salivary gland, adrenal gland, pancreas, ovary and fetal brain. High levels detected in liver, colon, small intestine, muscle, stomach, testis, placenta, thyroid, uterus, prostate, skin and PBL. {ECO:0000269|PubMed:11345586, ECO:0000269|PubMed:17088249}.

Abin-3 (H-101) - sc-367323 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Abin-3 (N-19) - sc-79827 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ABIN3 antibody - ab106452 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ABIN3 antibody (ab106452) at 1 µg/mlLane 1 : Human spleen tissue lysateLane 2 : Human spleen tissue lysate with blocking peptide Lysates/proteins at 15 µg per lane.

Anti-ABIN3 antibody - ab198697 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ABIN3 antibody (ab198697) at 1/200 dilution + mouse brain tissue lysate at 40 µg

Anti-ABIN3 antibody - ab113748 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ABIN3 antibody (ab113748) at 1 µg/mlLane 1 : Human spleen tissue lysateLane 2 : Human spleen tissue lysate with blocking peptide

Anti-ABIN3 antibody - N-terminal - ab174948 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of formalin fixed and paraffin embedded Human brain tissue labeling ABIN3 using ab174948 at a 1/50 dilution, followed by peroxidase conjugation of the secondary antibody and DAB staining.

Anti-TNIP3 Antibody (aa74-102, AP) - LS-C241971 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNIP3 Antibody (aa74-102, APC) - LS-C241972 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNIP3 Antibody (aa74-102, Biotin) - LS-C241973 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNIP3 Antibody (aa74-102, FITC) - LS-C241974 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNIP3 Antibody (aa74-102, PE) - LS-C241975 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNIP3 Antibody (aa74-102, Azide-free, HRP) - LS-C247101 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNIP3 Antibody (aa68-117) - LS-C152113 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TNIP3 antibody Western Blot of Fetal Lung.

Anti-TNIP3 Antibody (aa81-110) - LS-C325845 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNIP3 Antibody (aa74-102) - LS-C160083 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
TNIP3 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-TNIP3 Antibody (C-Terminus) IHC-plus™ - LS-B5021 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TNIP3 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5021 concentration 5 ug/ml.

TNIP3 Antibody - NBP1-77365 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: TNIP3 Antibody [NBP1-77365] - Human spleen tissue lysate with TNIP3 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

TNIP3 Antibody - NBP1-89305 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: TNIP3 Antibody [NBP1-89305] - Staining of human cell line U-251 MG shows positivity in nucleus but not nucleoli and cytoplasm.

TNIP3 Antibody - NBP1-72125 from Novus Biologicals

Prices $399.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: TNIP3 Antibody [NBP1-72125] - Staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

Anti-ABIN3 antibody produced in rabbit - SAB3500087 from Sigma-Aldrich

Prices $316.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ABIN3: <B>Cat. No. SAB3500087</B>: ABIN3 in human spleen tissue lysate with ABIN3 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

Anti-TNIP3 (91-105) antibody produced in rabbit - SAB1101898 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human TNIP3 was separated on SDS-PAGE, blotted with Anti-TNIP3 (91-105) (<B>Cat. No. SAB1101898</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000 <BR/>2. Antibody dilution 1:1,000 + TNIP3 immunizing peptide (human, 91-105)

Anti-TNIP3 (291-305) antibody produced in rabbit - SAB1101899 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human TNIP3 was separated on SDS-PAGE, blotted with Anti-TNIP3 (291-305) (<B>Cat. No. SAB1101899</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:500 <BR/>2. Antibody dilution 1:500 +TNIP3 immunizing peptide (human, 291-305)

Anti-TNIP3 antibody produced in rabbit - HPA043063 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TNIP3: <B>Cat. No. HPA043063</B>: Immunohistochemical staining of human colon shows strong cytoplasmic and membranous positivity in glandular cells.

TNIP3 Antibody - N-terminal region (ARP65979_P050) - ARP65979_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TNIP3 Antibody - N-terminal region (OAAB03010) - OAAB03010 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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