TNIP3

Gene Symbol	TNIP3
Entrez Gene	79931
Alt Symbol	ABIN-3, LIND
Species	Human
Gene Type	protein-coding
Description	TNFAIP3 interacting protein 3
Other Description	A20-binding inhibitor of NF-kappa-B activation 3|ABIN-3 beta|Listeria induced|TNFAIP3-interacting protein 3|TNFAIP3-interacting protein 3 beta|TNIP3 beta|listeria-induced gene protein
Swissprots	B4DVF5 B4E023 Q96PQ3 A1A574 Q96KP6 Q9H780 A8K2Z4
Accessions	EAX05263 EAX05264 EAX05265 Q96KP6 AF277289 AAL02151 AJ320534 CAC85929 AK024815 BAB15018 AK290409 BAF83098 AK301058 BAG62667 AK303192 BAG64285 BC128408 AAI28409 BP335455 CD367219 DC389224 EF585496 ABQ40006 XM_011532256 XP_011530558 XM_011532257 XP_011530559 XM_011532258 XP_011530560 XM_011532259 XP_011530561 NM_001128843 NP_001122315 NM_001244764 NP_001231693 NM_024873 NP_079149
Function	Binds to zinc finger protein TNFAIP3 and inhibits NF- kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13- acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding. {ECO:0000269|PubMed:17088249}.
Tissue Specificity	Highly expressed in lung, lymph node, thymus and fetal liver. Expressed at lower levels in bone marrow, brain, kidney, spleen, leukocytes and tonsils. Could be detected in heart, salivary gland, adrenal gland, pancreas, ovary and fetal brain. High levels detected in liver, colon, small intestine, muscle, stomach, testis, placenta, thyroid, uterus, prostate, skin and PBL. {ECO:0000269|PubMed:11345586, ECO:0000269|PubMed:17088249}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TNIP3 Antibody Blocking Peptide - LS-E30756 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TNIP3 Antibody Blocking Peptide - LS-E7901 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TNIP3 Antibody Blocking Peptide - LS-E24000 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TNIP3 Blocking Peptide - NBP1-77365PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

TNIP3-Antibody-N-term-Blocking-peptide - BP5598a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ABIN3 Peptide - GTX85255-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

TNIP3 Control Peptide - AP30005CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

ABIN3 Peptide - 5303P from ProSci Category Peptide Species Human

Recombinant Human TNFAIP3-interacting protein 3(TNIP3) - CSB-YP836243HU CSB-EP836243HU CSB-BP836243HU CSB-MP836243HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TNIP3 fusion protein - Ag24925 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

TNIP3 (transcript variant 2) - TP325469 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

TNIP3 fusion protein - Ag25006 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET30a Species Human

TNIP3 Protein - NBP1-89305PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

TNIP3 Peptide, Human - M34GP16386H from Creative Peptides Category Peptide Source Synthetic. Species Human

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