TNIP3

Gene Symbol	TNIP3
Entrez Gene	79931
Alt Symbol	ABIN-3, LIND
Species	Human
Gene Type	protein-coding
Description	TNFAIP3 interacting protein 3
Other Description	A20-binding inhibitor of NF-kappa-B activation 3|ABIN-3 beta|Listeria induced|TNFAIP3-interacting protein 3|TNFAIP3-interacting protein 3 beta|TNIP3 beta|listeria-induced gene protein
Swissprots	B4DVF5 B4E023 Q96PQ3 A1A574 Q96KP6 Q9H780 A8K2Z4
Accessions	EAX05263 EAX05264 EAX05265 Q96KP6 AF277289 AAL02151 AJ320534 CAC85929 AK024815 BAB15018 AK290409 BAF83098 AK301058 BAG62667 AK303192 BAG64285 BC128408 AAI28409 BP335455 CD367219 DC389224 EF585496 ABQ40006 XM_011532256 XP_011530558 XM_011532257 XP_011530559 XM_011532258 XP_011530560 XM_011532259 XP_011530561 NM_001128843 NP_001122315 NM_001244764 NP_001231693 NM_024873 NP_079149
Function	Binds to zinc finger protein TNFAIP3 and inhibits NF- kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13- acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding. {ECO:0000269|PubMed:17088249}.
Tissue Specificity	Highly expressed in lung, lymph node, thymus and fetal liver. Expressed at lower levels in bone marrow, brain, kidney, spleen, leukocytes and tonsils. Could be detected in heart, salivary gland, adrenal gland, pancreas, ovary and fetal brain. High levels detected in liver, colon, small intestine, muscle, stomach, testis, placenta, thyroid, uterus, prostate, skin and PBL. {ECO:0000269|PubMed:11345586, ECO:0000269|PubMed:17088249}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TNIP3 overexpression lysate - LY403041 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

TNIP3 overexpression lysate - LY427001 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

TNIP3 293 Cell Lysate - 402647 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

TNIP3 Overexpression Lysate (Native) - NBL1-17174 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

TNIP3 Overexpression Lysate (Native) - NBP2-09485 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

TNIP3 Over-expression Lysate Product - GWB-7F9827 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Panoply™ Human TNIP3 Knockdown Stable Cell Line - CSC-DC016386 from Creative biogene Category Cell Line Species Human

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