RHBDF1

Gene Symbol RHBDF1
Entrez Gene 64285
Alt Symbol C16orf8, Dist1, EGFR-RS, gene-89, gene-90, hDist1
Species Human
Gene Type protein-coding
Description rhomboid 5 homolog 1 (Drosophila)
Other Description epidermal growth factor receptor, related sequence|epidermal growth factor receptor-related protein|iRhom1|inactive rhomboid protein 1|p100hRho|rhomboid family 1|rhomboid family member 1
Swissprots Q1W6H2 Q4TT59 Q96S34 Q96CC6 Q04842 Q9H6E1
Accessions AAK61212 ABD95905 CAG27587 CAI95607 CAI95608 CAI95609 CAM26658 CAX15112 EAW85873 EAW85874 EAW85875 EAW85876 Q96CC6 AK026010 BAB15318 AK056708 BAG51794 AK225408 AK291177 BAF83866 AK304797 BAG65547 AK304812 BAG65562 AK309097 BC014425 AAH14425 BM830007 M99624 AAA02490 XM_005255494 XP_005255551 XM_005255498 XP_005255555 XM_006720921 XP_006720984 XM_011522598 XP_011520900 XM_011522599 XP_011520901 XM_011522600 XP_011520902 NM_022450 NP_071895
Function Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration. {ECO:0000269|PubMed:15965977, ECO:0000269|PubMed:18524845, ECO:0000269|PubMed:18832597, ECO:0000269|PubMed:21439629}.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Predominantly localized in the endoplasmic reticulum membrane.
Tissue Specificity Highly expressed in cerebellum, cerebrum, heart, skeletal muscle, placenta, pancreatic islet and testis. Detected at lower levels in colon, kidney, small intestine and lung. {ECO:0000269|PubMed:15965977, ECO:0000269|PubMed:8318735}.

Dist1 (P-14) - sc-164186 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Dist1 (Q-14) - sc-164187 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-RHBDF1 antibody - ab81342 from Abcam

Prices $379.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-RHBDF1 antibody (ab81342) at 1 µg/ml (in 5% skim milk / PBS buffer) + 721_B cell lysateSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-RHBDF1 Antibody (aa290-339) - LS-C81438 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

RHBDF1 Antibody - NBP1-59725 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RHBDF1 Antibody [NBP1-59725] - Sample Tissue: 721_B Whole Cell, Lane A: Primary Antibody, Lane B: Primary Antibody + Blocking Peptide, Primary Antibody Concentration: 1ug/ml, Peptide Concentration: 5ug/ml, Lysate Quantity: 25ug/lane/Lane, Gel Concentration: 0.

Anti-RHBDF1 antibody produced in rabbit - HPA015527 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RHBDF1: <B>Cat. No. HPA015527</B>: Immunohistochemical staining of human cervix, uterine shows moderate cytoplasmic positivity in squamous epithelial cells.

Anti-RHBDF1 antibody produced in rabbit - SAB2101999 from Sigma-Aldrich

Prices $347.50
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RHBDF1: <B>Cat. No.SAB2101999</B>: RHBDF1 in 721_B cell lysate with RHBDF1 antibody at 1.0 μg/mL.

RHBDF1 antibody - N-terminal region (ARP49721_P050) - ARP49721_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RHBDF1 antibody - 70R-6632 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

RHBDF1 Antibody - 26-447 from ProSci

Prices $315.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Antibody used in WB on Human 721_B at 0.2-1 ug/ml.

HER2 (Phospho-Thr686) Polyclonal Antibody - PA000341-A0918 from Syd Labs

Prices $150.00, $250.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

HER2 (Phospho-Tyr1221/Tyr1222) Polyclonal Antibody - PA000341-A7103 from Syd Labs

Prices $150.00, $250.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

HER2 (Phospho-Tyr1248) Polyclonal Antibody - PA000341-A7104 from Syd Labs

Prices $150.00, $250.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

HER2 (Phospho-Tyr877) Polyclonal Antibody - PA000341-A7105 from Syd Labs

Prices $150.00, $250.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

HER2 (Phospho-Tyr1112) Polyclonal Antibody - PA000341-A8039 from Syd Labs

Prices $150.00, $250.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

HER2 (Ab-686) Polyclonal Antibody - PA000341-B0918 from Syd Labs

Prices $150.00, $250.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

HER2 (Ab-686) Polyclonal Antibody - PA000341-B0942 from Syd Labs

Prices $150.00, $250.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

HER2 (Ab-1139) Polyclonal Antibody - PA000341-B0943 from Syd Labs

Prices $150.00, $250.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

HER2 (Ab-1221/1222) Polyclonal Antibody - PA000341-B7103 from Syd Labs

Prices $150.00, $250.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

HER2 (Ab-1248) Polyclonal Antibody - PA000341-B7104 from Syd Labs

Prices $150.00, $250.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

HER2 (Ab-877) Polyclonal Antibody - PA000341-B7105 from Syd Labs

Prices $150.00, $250.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

HER2 (Ab-1112) Polyclonal Antibody - PA000341-B8039 from Syd Labs

Prices $150.00, $250.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

HER2 Polyclonal Antibody - PA000341-C12903 from Syd Labs

Prices $150.00, $250.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

HER2 Polyclonal Antibody - PA000341-R12-2872 from Syd Labs

Prices $150.00, $250.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

ERBB2 Monoclonal Antibody - PA000341-ANT-033 from Syd Labs

Prices $160.00, $600.00
Sizes 15 µg, 100 µg
Host Mouse
Clonality Monoclonal
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