Gene Symbol | ATP5E |
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Entrez Gene | 514 |
Alt Symbol | ATPE, MC5DN3 |
Species | Human |
Gene Type | protein-coding |
Description | ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit |
Other Description | ATP synthase subunit epsilon, mitochondrial|F(0)F(1)-ATPase|H(+)-transporting two-sector ATPase|mitochondrial ATP synthase epsilon chain|mitochondrial ATPase |
Swissprots | Q53XU6 P56381 E1P5H6 B2RDD0 |
Accessions | EAW75444 EAW75445 EAW75446 P56381 AF052955 AAF72736 AF077045 AAD27778 AK026556 AK315493 BAG37877 BC001690 AAH01690 BC003671 AAH03671 BC070167 BC105811 AAI05812 BT007293 AAP35957 CB106920 DA202623 NM_006886 NP_008817 |
Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion. Mitochondrion inner membrane. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Alzheimer's disease, Huntington's disease, Oxidative phosphorylation |
ATP5E (A-11) - sc-393695 from Santa Cruz Biotechnology
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ATP5E (A-12) - sc-393696 from Santa Cruz Biotechnology
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ATP5E (C-19) - sc-49166 from Santa Cruz Biotechnology
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ATP5E (FL-51) - sc-134729 from Santa Cruz Biotechnology
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ATP5E (Z88) - sc-81874 from Santa Cruz Biotechnology
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Anti-ATP5E antibody - ab54879 from Abcam
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Anti-ATP5E antibody [2F3] - ab109992 from Abcam
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Anti-ATP5E Antibody (clone 2F3) IHC-plus™ - LS-B4287 from LifeSpan Bioscience
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Anti-ATP5E Antibody (aa1-50, DY650) - LS-C143273 from LifeSpan Bioscience
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Anti-ATP5E Antibody (aa1-50) - LS-C143271 from LifeSpan Bioscience
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Anti-ATP5E Antibody (aa1-50, Biotin) - LS-C143272 from LifeSpan Bioscience
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Anti-ATP5E Antibody (aa1-50, DY488) - LS-C143274 from LifeSpan Bioscience
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Anti-ATP5E Antibody (aa1-50, HRP) - LS-C143275 from LifeSpan Bioscience
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Anti-ATP5E Antibody (aa1-50, DY550) - LS-C143276 from LifeSpan Bioscience
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Anti-ATP5E Antibody (aa1-50) - LS-C143277 from LifeSpan Bioscience
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Anti-ATP5E Antibody (aa1-50, Biotin) - LS-C143278 from LifeSpan Bioscience
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Anti-ATP5E Antibody (aa1-50, DY650) - LS-C143279 from LifeSpan Bioscience
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Anti-ATP5E Antibody (aa1-50, HRP) - LS-C143281 from LifeSpan Bioscience
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Anti-ATP5E Antibody (aa1-50, DY488) - LS-C143280 from LifeSpan Bioscience
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Anti-ATP5E Antibody (aa1-50, DY550) - LS-C143282 from LifeSpan Bioscience
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ATP5E Antibody - NBP1-42805 from Novus Biologicals
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ATP5E Antibody (2F3) - H00000514-M01 from Novus Biologicals
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ATP5E Antibody [HRP] - NBP1-42805H from Novus Biologicals
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ATP5E Antibody [DyLight 550] - NBP1-42805R from Novus Biologicals
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ATP5E Antibody [DyLight 488] - NBP1-42805G from Novus Biologicals
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