ATP5E

Gene Symbol	ATP5E
Entrez Gene	514
Alt Symbol	ATPE, MC5DN3
Species	Human
Gene Type	protein-coding
Description	ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
Other Description	ATP synthase subunit epsilon, mitochondrial|F(0)F(1)-ATPase|H(+)-transporting two-sector ATPase|mitochondrial ATP synthase epsilon chain|mitochondrial ATPase
Swissprots	Q53XU6 P56381 E1P5H6 B2RDD0
Accessions	EAW75444 EAW75445 EAW75446 P56381 AF052955 AAF72736 AF077045 AAD27778 AK026556 AK315493 BAG37877 BC001690 AAH01690 BC003671 AAH03671 BC070167 BC105811 AAI05812 BT007293 AAP35957 CB106920 DA202623 NM_006886 NP_008817
Function	Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits (By similarity). {ECO:0000250}.
Subcellular Location	Mitochondrion. Mitochondrion inner membrane.
Tissue Specificity	Ubiquitous.
Top Pathways	Alzheimer's disease, Huntington's disease, Oxidative phosphorylation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

ATP5E overexpression lysate - LY416365 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

ATP5E 293 Cell Lysate - 407650 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

ATP5E Overexpression Lysate (Native) - NBL1-07821 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

ATP5E Overexpression Lysate (Native) - NBP2-09084 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

ATP5E Overexpression Lysate (Native) - NBP2-08968 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

ATP5E Over-expression Lysate Product - GWB-164210 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

ATP5E-knockout Cell lysate - LC810018 from Acris Antibodies Category Cell Lysate Prices $495.00 Sizes 100 µg

Panoply™ Human ATP5E Knockdown Stable Cell Line - CSC-DC001156 from Creative biogene Category Cell Line Species Human

Human ATP5E Knockout Cell Line-HeLa - CSC-RT0885 from Creative biogene Category Cell Line Species Human

ATP5E KO Cell Lysate-HeLa - CLKO-1716 from Creative biogene Category Cell Lysate

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