ATP5E

Gene Symbol	ATP5E
Entrez Gene	514
Alt Symbol	ATPE, MC5DN3
Species	Human
Gene Type	protein-coding
Description	ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
Other Description	ATP synthase subunit epsilon, mitochondrial|F(0)F(1)-ATPase|H(+)-transporting two-sector ATPase|mitochondrial ATP synthase epsilon chain|mitochondrial ATPase
Swissprots	Q53XU6 P56381 E1P5H6 B2RDD0
Accessions	EAW75444 EAW75445 EAW75446 P56381 AF052955 AAF72736 AF077045 AAD27778 AK026556 AK315493 BAG37877 BC001690 AAH01690 BC003671 AAH03671 BC070167 BC105811 AAI05812 BT007293 AAP35957 CB106920 DA202623 NM_006886 NP_008817
Function	Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits (By similarity). {ECO:0000250}.
Subcellular Location	Mitochondrion. Mitochondrion inner membrane.
Tissue Specificity	Ubiquitous.
Top Pathways	Alzheimer's disease, Huntington's disease, Oxidative phosphorylation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human ATP5E full length protein - ab157933 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Recombinant Human ATP5E Protein - H00000514-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ATP synthase subunit epsilon - H00000514-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ATP synthase subunit epsilon - H00000514-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ATP5E fusion protein - Ag7672 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human ATP5E, GST-tagged - ATP5E-10018H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human ATP synthase subunit epsilon, mitochondrial(ATP5E) - CSB-YP002356HU CSB-EP002356HU CSB-BP002356HU CSB-MP002356HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ATP synthase subunit epsilon - TP310456 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ATP synthase subunit epsilon, mitochondrial(ATP5E) , Recombinant Protein - MBS951972 from MyBioSource Category Protein Prices $1,075.00, $1,075.00, $1,530.00, $1,530.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ATP5E Protein - NBP2-14330PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

ATP5E-Blocking-Peptide-C-Term - BP21888b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ATP5E Peptide, Human - M34GP01156H from Creative Peptides Category Peptide Source Synthetic. Species Human

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