NPPB

Gene Symbol	NPPB
Entrez Gene	4879
Alt Symbol	BNP
Species	Human
Gene Type	protein-coding
Description	natriuretic peptide B
Other Description	brain type natriuretic peptide|gamma-brain natriuretic peptide|natriuretic peptide precursor B|natriuretic peptides B|natriuretic protein
Swissprots	Q9P2Q7 B0ZBE9 P16860 Q6FGY0
Accessions	AAA35603 ACA05917 BAA04067 BAA90441 BAD06457 BAF64842 EAW71718 EAW71719 P16860 AJ708502 BC025785 AAH25785 CR541976 CAG46774 CR542003 CAG46800 M25296 AAA36355 NM_002521 NP_002512
Function	Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. {ECO:0000269|PubMed:1672777}.
Subcellular Location	Secreted.
Tissue Specificity	Brain and also in atria, but at much lower levels than ANP.
Top Pathways	cGMP-PKG signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-NPPB-cDNA-Clone - DC05538 from Abgent, a WuXi AppTec company Prices $180.90 Sizes 10 µg Species Human Accession BC025785

NPPB - MBS1278393 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC025785

Human NPPB Gene ORF cDNA clone in cloning vector - HG13644-G from Sino Biological Species Human

Human NPPB Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13644-ACR from Sino Biological Species Human

Human NPPB Gene ORF cDNA clone expression plasmid, N-HA tag - HG13644-NY from Sino Biological Species Human

Human NPPB Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13644-NF from Sino Biological Species Human

Human NPPB Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13644-NM from Sino Biological Species Human

Human NPPB Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13644-CF from Sino Biological Species Human

Human NPPB Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13644-CM from Sino Biological Species Human

Human NPPB Gene ORF cDNA clone expression plasmid, N-His tag - HG13644-NH from Sino Biological Species Human

Human NPPB Gene ORF cDNA clone expression plasmid, C-HA tag - HG13644-CY from Sino Biological Species Human

Human NPPB Gene ORF cDNA clone expression plasmid - HG13644-G-N from Sino Biological Species Human

Human NPPB Gene ORF cDNA clone expression plasmid, C-His tag - HG13644-CH from Sino Biological Species Human

Human NPPB Gene ORF cDNA clone expression plasmid - HG13644-UT from Sino Biological Species Human

Human NPPB Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13644-ACG from Sino Biological Species Human

Human NPPB ORF Clone (BC025785) - CDCS410827 from Creative biogene Species Human Accession P16860

Human NPPB ORF clone (BC025785) - CDCB159608 from Creative biogene Species Human

Human NPPB Gene cDNA Clone - orb144484 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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