NPPB

Gene Symbol NPPB
Entrez Gene 4879
Alt Symbol BNP
Species Human
Gene Type protein-coding
Description natriuretic peptide B
Other Description brain type natriuretic peptide|gamma-brain natriuretic peptide|natriuretic peptide precursor B|natriuretic peptides B|natriuretic protein
Swissprots Q9P2Q7 B0ZBE9 P16860 Q6FGY0
Accessions AAA35603 ACA05917 BAA04067 BAA90441 BAD06457 BAF64842 EAW71718 EAW71719 P16860 AJ708502 BC025785 AAH25785 CR541976 CAG46774 CR542003 CAG46800 M25296 AAA36355 NM_002521 NP_002512
Function Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. {ECO:0000269|PubMed:1672777}.
Subcellular Location Secreted.
Tissue Specificity Brain and also in atria, but at much lower levels than ANP.
Top Pathways cGMP-PKG signaling pathway

BNP CRISPR/Cas9 KO Plasmid (h) - sc-402447 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BNP HDR Plasmid (h) - sc-402447-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BNP Double Nickase Plasmid (h) - sc-402447-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BNP Double Nickase Plasmid (h2) - sc-402447-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BNP CRISPR Activation Plasmid (h) - sc-402447-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BNP CRISPR Activation Plasmid (h2) - sc-402447-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BNP Lentiviral Activation Particles (h) - sc-402447-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BNP Lentiviral Activation Particles (h2) - sc-402447-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BNP siRNA (h) - sc-43636 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BNP shRNA Plasmid (h) - sc-43636-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BNP shRNA (h) Lentiviral Particles - sc-43636-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BNP RNAi - H00004879-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN15465 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15465 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01108 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01108

NPPB siRNA (Human) - CRH3240 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NPPB (NM_002521.2) - SHH354368 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human NPPB(NM_002521.2) - SHG103033 from Creative biogene

Category siRNA
Species Reactivities Human

Human NPPB siRNA - orb263742 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NPPB shRNA Plasmid (Human) - CHH3240 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NPPB miRNA 3'UTR clone - MiUTR1H-06879 from Creative biogene

Species Reactivities Human
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