FNDC5

Gene Symbol	FNDC5
Entrez Gene	252995
Alt Symbol	FRCP2, irisin
Species	Human
Gene Type	protein-coding
Description	fibronectin type III domain containing 5
Other Description	fibronectin type III domain-containing protein 5|fibronectin type III repeat-containing protein 2
Swissprots	D3DPQ6 A6NMC9 Q8NAU1 Q6P6D9 Q7Z676
Accessions	EAX07499 EAX07500 EAX07501 EAX07502 Q8NAU1 AK092102 BAC03806 BC007548 BC033123 BC062297 AAH62297 BE502835 BX537781 CAD97840 CV815003 DA393478 NM_001171940 NP_001165411 NM_001171941 NP_001165412 NM_153756 NP_715637
Function	Irisin: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue. {ECO:0000269|PubMed:24040023}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:22237023}; Single-pass type I membrane protein {ECO:0000269|PubMed:22237023}. Peroxisome membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Imported in peroxisomes through the PEX5 receptor pathway. {ECO:0000250}.
Tissue Specificity	Widely expressed, with highest levels in heart. Very low expression, if any, in colon, pancreas and spleen. {ECO:0000269|PubMed:24040023}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FNDC5 full length protein - ab184599 from Abcam Category Protein Source HEK 293 cells Species Human

Human FNDC5 full length protein - ab132900 from Abcam Category Protein Source Wheat germ Species Human

Human FNDC5 full length protein - ab193867 from Abcam Category Protein Source HEK 293 cells Species Human

Human FNDC5 protein fragment - ab133147 from Abcam Category Protein Source E. coli Species Human

Human FNDC5 protein fragment - ab133144 from Abcam Category Protein Source E. coli Species Human

Human FNDC5 protein fragment - ab134851 from Abcam Category Protein Source E. coli Species Human

Mouse FNDC5 peptide - ab153677 from Abcam Category Peptide

Recombinant Human Irisin/FNDC5 Protein - H00252995-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Irisin/FNDC5 Protein - H00252995-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

FNDC5-Antibody-C-term-Blocking-Peptide - BP8746b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Irisin (Tagless) protein - orb180476 from Biorbyt Category Protein Prices $544.00 Sizes 100 µg Source E. coli Species Human

Human FNDC5 protein - orb191165 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

Human FNDC5 protein - orb191123 from Biorbyt Category Protein Prices $230.00, $442.00 Sizes 2 μg, 10 μg Source Yeast Species Human

Irisin (His-Tagged) protein - orb180477 from Biorbyt Category Protein Prices $476.00 Sizes 100 µg Source E. coli Species Human

Human FNDC5 Protein - abx066629 from Abbexa Category Protein Source E.coli Species Human

Human FNDC5 Protein - abx066628 from Abbexa Category Protein Source E.coli Species Human

FNDC5 - H00252995-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

FNDC5 - H00252995-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

FNDC5 - H00252995-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

FNDC5 - H00252995-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Fibronectin Type III Domain Containing Protein 5 - 20-9554 from ARP American Research Products Category Protein Prices $507.00 Sizes 50 µg Source E.coli Species Human

Fibronectin Type III Domain Containing Protein 5 - 20-9555 from ARP American Research Products Category Protein Prices $507.00 Sizes 50 µg Source E.coli Species Human

FNDC5 fusion protein - Ag21195 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human FNDC5, StrepII-tagged - FNDC5-253H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Fibronectin Type III Domain Containing Protein 5 (FNDC5) - RPN576Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

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