FNDC5

Gene Symbol FNDC5
Entrez Gene 252995
Alt Symbol FRCP2, irisin
Species Human
Gene Type protein-coding
Description fibronectin type III domain containing 5
Other Description fibronectin type III domain-containing protein 5|fibronectin type III repeat-containing protein 2
Swissprots D3DPQ6 A6NMC9 Q8NAU1 Q6P6D9 Q7Z676
Accessions EAX07499 EAX07500 EAX07501 EAX07502 Q8NAU1 AK092102 BAC03806 BC007548 BC033123 BC062297 AAH62297 BE502835 BX537781 CAD97840 CV815003 DA393478 NM_001171940 NP_001165411 NM_001171941 NP_001165412 NM_153756 NP_715637
Function Irisin: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue. {ECO:0000269|PubMed:24040023}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:22237023}; Single-pass type I membrane protein {ECO:0000269|PubMed:22237023}. Peroxisome membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Imported in peroxisomes through the PEX5 receptor pathway. {ECO:0000250}.
Tissue Specificity Widely expressed, with highest levels in heart. Very low expression, if any, in colon, pancreas and spleen. {ECO:0000269|PubMed:24040023}.

Anti-FNDC5 antibody - ab131390 from Abcam

Prices $378.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-FNDC5 antibody (ab131390) at 1 µg/mlLane 1 : K562 (Human erythromyeloblastoid leukemia cell line) Whole Cell LysateLane 2 : C2C12 (Mouse myoblast cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-FNDC5 antibody [EPR12209] - ab174833 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12209
Anti-FNDC5 antibody [EPR12209] (ab174833) at 1/1000 dilution (purified) + Human fetal muscle tissue lysate at 10 µgSecondaryHRP-conjugated anti-rabbit IgG, specific to the non-reduced form of IgG at 1/1000 dilution

Anti-FNDC5 antibody - C-terminal - ab181884 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FNDC5 / Irisin Antibody (aa2-137, Biotin) - LS-C297398 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FNDC5 / Irisin Antibody - LS-C305984 from LifeSpan Bioscience

Prices $545.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-FNDC5 / Irisin Antibody (aa2-137, FITC) - LS-C304999 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FNDC5 / Irisin Antibody (Biotin) - LS-C345061 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FNDC5 / Irisin Antibody - LS-C344845 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FNDC5 / Irisin Antibody (aa2-137) - LS-C293925 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant FNDC5.

Irisin/FNDC5 Antibody - NBP2-14024 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FNDC5 Polyclonal Antibody - bs-8486R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ANTI-FNDC5 (C-TERM) antibody produced in rabbit - SAB1301655 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal

FNDC5 Antibody - abx104499 from Abbexa

Host Rabbit
Clonality Polyclonal

FNDC5 antibody - 23995-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human skeletal muscle slide using 23995-1-AP( FNDC5 Antibody) at dilution of 1:50

Anti-Fibronectin Type III Domain Protein 5 - 20-5640 from ARP American Research Products

Prices $389.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-Irisin (IN102) - 23-10027 from ARP American Research Products

Prices $159.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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