FNDC5

Gene Symbol FNDC5
Entrez Gene 252995
Alt Symbol FRCP2, irisin
Species Human
Gene Type protein-coding
Description fibronectin type III domain containing 5
Other Description fibronectin type III domain-containing protein 5|fibronectin type III repeat-containing protein 2
Swissprots D3DPQ6 A6NMC9 Q8NAU1 Q6P6D9 Q7Z676
Accessions EAX07499 EAX07500 EAX07501 EAX07502 Q8NAU1 AK092102 BAC03806 BC007548 BC033123 BC062297 AAH62297 BE502835 BX537781 CAD97840 CV815003 DA393478 NM_001171940 NP_001165411 NM_001171941 NP_001165412 NM_153756 NP_715637
Function Irisin: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue. {ECO:0000269|PubMed:24040023}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:22237023}; Single-pass type I membrane protein {ECO:0000269|PubMed:22237023}. Peroxisome membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Imported in peroxisomes through the PEX5 receptor pathway. {ECO:0000250}.
Tissue Specificity Widely expressed, with highest levels in heart. Very low expression, if any, in colon, pancreas and spleen. {ECO:0000269|PubMed:24040023}.

FNDC5 CRISPR/Cas9 KO Plasmid (h) - sc-415178 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FNDC5 HDR Plasmid (h) - sc-415178-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FNDC5 Double Nickase Plasmid (h) - sc-415178-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FNDC5 Double Nickase Plasmid (h2) - sc-415178-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FNDC5 CRISPR Activation Plasmid (h) - sc-415178-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FNDC5 CRISPR Activation Plasmid (h2) - sc-415178-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FNDC5 Lentiviral Activation Particles (h) - sc-415178-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FNDC5 Lentiviral Activation Particles (h2) - sc-415178-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FNDC5 siRNA (h) - sc-78601 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FNDC5 shRNA Plasmid (h) - sc-78601-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FNDC5 shRNA (h) Lentiviral Particles - sc-78601-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU071871 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8858 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8858 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

FNDC5 siRNA (Human) - CRJ6632 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FNDC5 - MBS8212337 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FNDC5 (NM_153756.2) - SHH296165 from Creative biogene

Category siRNA
Species Reactivities Human

FNDC5 shRNA Plasmid (Human) - CHJ6632 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FNDC5 miRNA 3'UTR clone - MiUTR4H-TG11238 from Creative biogene

Species Reactivities Human
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