DNAJB11

Gene Symbol DNAJB11
Entrez Gene 51726
Alt Symbol ABBP-2, ABBP2, DJ9, Dj-9, EDJ, ERdj3, ERj3, ERj3p, PRO1080, UNQ537
Species Human
Gene Type protein-coding
Description DnaJ (Hsp40) homolog, subfamily B, member 11
Other Description APOBEC1-binding protein 2|DnaJ protein 9|ER-associated DNAJ protein 3|ER-associated Hsp40 co-chaperone|ER-resident protein ERdj3|PWP1-interacting protein 4|dnaJ homolog subfamily B member 11|endoplasmic reticulum DNA J domain-containing protein 3
Swissprots Q6IAQ8 Q542Y5 Q542Y9 Q96JC6 Q9UBS4
Accessions CAI72116 EAW78190 Q9UBS4 AB028859 BAA88307 AF228505 AAF61711 AF277317 AAK69110 AI446699 AJ250137 CAB65118 AK075300 BAC11533 AK075430 BAC11617 AK124289 BAG54025 AK301292 BAG62850 AY359043 AAQ89402 BC001144 AAH01144 BC046500 BM754506 BT007063 AAP35712 CR457096 CAG33377 DA058195 DQ890601 ABM92218 DQ893869 ABM84795 NM_016306 NP_057390
Function Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. {ECO:0000269|PubMed:10827079, ECO:0000269|PubMed:15525676}.
Subcellular Location Endoplasmic reticulum lumen {ECO:0000269|PubMed:10827079, ECO:0000269|PubMed:15195998, ECO:0000269|PubMed:15525676, ECO:0000269|PubMed:15544163}. Note=Associated with the ER membrane in a C-terminally epitope- tagged construct.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:10827079, ECO:0000269|PubMed:11584023, ECO:0000269|PubMed:15525676}.
Top Pathways Protein processing in endoplasmic reticulum

ERdj3 (C-7) - sc-271240 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ERdj3 (C-7): sc-271240. Western blot analysis of ERdj3 expression in Hep G2 (A) and Raji (B) whole cell lysates.

ERdj3 (H-130) - sc-99208 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ERdj3 (H-130): sc-99208. Western blot analysis of ERdj3 expression in non-transfected 293T: sc-117752 (A), human ERdj3 transfected 293T: sc-173247 (B) and Hep G2 (C) whole cell lysates.

ERdj3 (C-19) - sc-46944 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ERdj3 (N-16) - sc-46945 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ERdj3 (N-16): sc-46945. Western blot analysis of ERdj3 expression in Hep G2 (A), Raji (B) and HeLa (C) whole cell lysates and mouse placenta tissue extract (D).

Anti-DNAJB11 antibody - ab75107 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DNAJB11 antibody (ab75107) at 1/500 dilutionLane 1 : extracts from HeLa cellsLane 2 : extracts from HUVEC cellsLane 3 : extracts from COLO cellsLane 4 : extracts from MCF-7 cellsLane 5 : extracts from HeLa cells with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-DNAJB11 antibody - ab112959 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-DNAJB11 antibody (ab112959) at 1/100 dilution + NCI-H460 cell lysate at 35 µg

Anti-DNAJB11 Antibody (aa63-92, AP) - LS-C222140 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DNAJB11 Antibody (aa63-92, APC) - LS-C222141 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DNAJB11 Antibody (C-Terminus) - LS-C81013 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-DNAJB11 Antibody (aa63-92, FITC) - LS-C222144 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DNAJB11 Antibody (aa63-92, Biotin) - LS-C222143 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DNAJB11 Antibody (aa63-92, Azide-free, HRP) - LS-C222142 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DNAJB11 Antibody (aa63-92, PE) - LS-C222145 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DNAJB11 Antibody (aa31-80) IHC-plus™ - LS-B9732 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-DNAJB11 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9732 concentration 10 ug/ml.

Anti-DNAJB11 Antibody (aa62-92) - LS-C320882 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DNAJB11 Antibody (Lys66) - LS-C177366 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of ERdj3 (K66) pAb in paraffin-embedded human heart tissue.

Anti-DNAJB11 Antibody (aa63-92) - LS-C167463 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
DNAJB11 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human placenta tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

DNAJB11 Antibody - NBP1-84899 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DNAJB11 Antibody [NBP1-84899] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.

DNAJB11 Antibody - NBP1-00814 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Western Blot: ERdj3 Antibody [NBP1-00814] - Western blot (WB) analysis of ERdj3 (K66) antibody in extracts from HeLa cells

DNAJB11 Antibody - NBP1-84900 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DNAJB11 Antibody [NBP1-84900] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

Anti-DNAJB11 antibody produced in rabbit - HPA017051 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-DNAJB11: <B>Cat. No. HPA017051</B>: Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in Syncytiotrophoblasts.

Anti-DNAJB11 antibody produced in rabbit - HPA010814 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-DNAJB11: <B>Cat. No. HPA010814</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human testis tissue showing cytoplasmic positivity in cells in seminiferus ducts and in Leydig cells.

Anti-DNAJB11 antibody produced in rabbit - SAB2100605 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-DNAJB11: <B>Cat. No.SAB2100605</B>: DNAJB11 in HepG2 cell lysate with DNAJB11 antibody at 1.0 μg/mL.

Anti-DNAJB11 antibody produced in rabbit - SAB4502165 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-DNAJB11: <B>Cat. No. SAB4502165</B>: Immunohistochemistry analysis of paraffin-embedded human heart tissue using Anti-DNAJB11 antibody. Cells on the left were treated with the Anti-DNAJB11 antibody. Cells on the right (negative control) were treated with both Anti-DNAJB11 antibody and the synthesized immunogen peptide.

DNAJB11 antibody - C-terminal region (ARP47245_P050) - ARP47245_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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