DNAJB11

Gene Symbol DNAJB11
Entrez Gene 51726
Alt Symbol ABBP-2, ABBP2, DJ9, Dj-9, EDJ, ERdj3, ERj3, ERj3p, PRO1080, UNQ537
Species Human
Gene Type protein-coding
Description DnaJ (Hsp40) homolog, subfamily B, member 11
Other Description APOBEC1-binding protein 2|DnaJ protein 9|ER-associated DNAJ protein 3|ER-associated Hsp40 co-chaperone|ER-resident protein ERdj3|PWP1-interacting protein 4|dnaJ homolog subfamily B member 11|endoplasmic reticulum DNA J domain-containing protein 3
Swissprots Q6IAQ8 Q542Y5 Q542Y9 Q96JC6 Q9UBS4
Accessions CAI72116 EAW78190 Q9UBS4 AB028859 BAA88307 AF228505 AAF61711 AF277317 AAK69110 AI446699 AJ250137 CAB65118 AK075300 BAC11533 AK075430 BAC11617 AK124289 BAG54025 AK301292 BAG62850 AY359043 AAQ89402 BC001144 AAH01144 BC046500 BM754506 BT007063 AAP35712 CR457096 CAG33377 DA058195 DQ890601 ABM92218 DQ893869 ABM84795 NM_016306 NP_057390
Function Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. {ECO:0000269|PubMed:10827079, ECO:0000269|PubMed:15525676}.
Subcellular Location Endoplasmic reticulum lumen {ECO:0000269|PubMed:10827079, ECO:0000269|PubMed:15195998, ECO:0000269|PubMed:15525676, ECO:0000269|PubMed:15544163}. Note=Associated with the ER membrane in a C-terminally epitope- tagged construct.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:10827079, ECO:0000269|PubMed:11584023, ECO:0000269|PubMed:15525676}.
Top Pathways Protein processing in endoplasmic reticulum

DNAJB11-Over-expression-Lysate - LY14042a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag DNAJB11 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the DNAJB11 gene.

DNAJB11 overexpression lysate - LY402537 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

DNAJB11 293 Cell Lysate - 402220 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

DNAJB11 Overexpression Lysate (Native) - NBL1-09933 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: DNAJB11 Overexpression Lysate (Adult Normal) [NBL1-09933] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DNAJB11.

ERdj3 (h2): 293T Lysate - sc-173247 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

DNAJB11 Over-expression Lysate Product - GWB-E0672A from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human DNAJB11 Knockdown Stable Cell Line - CSC-DC004403 from Creative biogene

Category Cell Line
Species Human
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