Gene Symbol | DNAJB11 |
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Entrez Gene | 51726 |
Alt Symbol | ABBP-2, ABBP2, DJ9, Dj-9, EDJ, ERdj3, ERj3, ERj3p, PRO1080, UNQ537 |
Species | Human |
Gene Type | protein-coding |
Description | DnaJ (Hsp40) homolog, subfamily B, member 11 |
Other Description | APOBEC1-binding protein 2|DnaJ protein 9|ER-associated DNAJ protein 3|ER-associated Hsp40 co-chaperone|ER-resident protein ERdj3|PWP1-interacting protein 4|dnaJ homolog subfamily B member 11|endoplasmic reticulum DNA J domain-containing protein 3 |
Swissprots | Q6IAQ8 Q542Y5 Q542Y9 Q96JC6 Q9UBS4 |
Accessions | CAI72116 EAW78190 Q9UBS4 AB028859 BAA88307 AF228505 AAF61711 AF277317 AAK69110 AI446699 AJ250137 CAB65118 AK075300 BAC11533 AK075430 BAC11617 AK124289 BAG54025 AK301292 BAG62850 AY359043 AAQ89402 BC001144 AAH01144 BC046500 BM754506 BT007063 AAP35712 CR457096 CAG33377 DA058195 DQ890601 ABM92218 DQ893869 ABM84795 NM_016306 NP_057390 |
Function | Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. {ECO:0000269|PubMed:10827079, ECO:0000269|PubMed:15525676}. |
Subcellular Location | Endoplasmic reticulum lumen {ECO:0000269|PubMed:10827079, ECO:0000269|PubMed:15195998, ECO:0000269|PubMed:15525676, ECO:0000269|PubMed:15544163}. Note=Associated with the ER membrane in a C-terminally epitope- tagged construct. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:10827079, ECO:0000269|PubMed:11584023, ECO:0000269|PubMed:15525676}. |
Top Pathways | Protein processing in endoplasmic reticulum |
Human DNAJB11 full length protein - ab105636 from Abcam
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DNAJB11 Antibody Blocking Peptide - LS-E1812 from LifeSpan Bioscience
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DNAJB11 Antibody Blocking Peptide - LS-E17132 from LifeSpan Bioscience
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Recombinant Human DNAJB11 Protein - H00051726-P01 from Novus Biologicals
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Recombinant Human DNAJB11 Protein - NBP1-51055 from Novus Biologicals
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DNAJB11-Antibody-N-term-Blocking-peptide - BP12621a from Abgent, a WuXi AppTec company
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DNAJB11 Protein (OPPA00038) - OPPA00038 from Aviva Systems Biology
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Human DNAJB11 protein - orb168239 from Biorbyt
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DNAJB11 peptide - orb218546 from Biorbyt
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DNAJB11 Blocking Peptide - 33R-2868 from Fitzgerald
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DNAJB11 protein (His tag) - 80R-1743 from Fitzgerald
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DNAJB11 Blocking Peptide - abx063877 from Abbexa
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DNAJB11 (23-358, His-tag) - AR09925PU-N from Acris Antibodies
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DNAJB11 (23-358, His-tag) - AR09925PU-S from Acris Antibodies
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DNAJB11 - H00051726-P01-10 from Acris Antibodies
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DNAJB11 - H00051726-P01-25 from Acris Antibodies
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DNAJB11, 23-358aa, Human, His tag, E.coli - 01-P0985 from ARP American Research Products
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DNAJB11 fusion protein - Ag7758 from Proteintech Group
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DNAJB11 fusion protein - Ag7832 from Proteintech Group
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DNAJB11 Human - HYPS-049 from NeoScientific
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Recombinant Human DNAJB11 Protein - BP001977-HSP-042 from Syd Labs
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DNAJB11 Human Protein - GWB-BSP721 from Genway Biotech
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DNAJB11, 23-358aa, Recombinant Protein - GWB-P1053M from Genway Biotech
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Recombinant Human DNAJB11, His-tagged - DNAJB11-3490H from Creative Biomart
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Recombinant Human DNAJB11, His-tagged - DNAJB11-28366TH from Creative Biomart
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