KCTD11

Gene Symbol KCTD11
Entrez Gene 147040
Alt Symbol C17orf36, KCASH1, REN, REN/KCTD11
Species Human
Gene Type protein-coding
Description potassium channel tetramerization domain containing 11
Other Description BTB/POZ domain-containing protein KCTD11|potassium channel tetramerisation domain containing 11|retinoic acid, EGF, NGF induced gene protein|retinoic acid, EGF, NGF induced gene/potassium channel tetramerization domain containing 11
Swissprots Q693B1 B3KPE0
Accessions EAW90208 Q693B1 AK056227 BAG51652 AY646650 AAT75307 BC019929 AAH19929 BC063604 BC103744 BC110598 AAI10599 NM_001002914 NP_001002914
Function Plays a role as a marker and a regulator of neuronal differentiation; Up-regulated by a variety of neurogenic signals, such as retinoic acid, epidermal growth factor/EGF and NGFB/nerve growth factor. Induces apoptosis, growth arrest and the expression of cyclin-dependent kinase inhibitor CDKN1B. Plays a role as a tumor repressor and inhibits cell growth and tumorigenicity of medulloblastoma (MDB). Acts as an E3 ubiquitin-protein ligase towards HDAC1, leading to its proteasomal degradation. Functions as antagonist of the Hedgehog pathway on cell proliferation and differentiation by affecting the nuclear transfer of transcrition factor GLI1, thus maintaining cerebellar granule cells in undifferentiated state, this effect probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. When knock- down, Hedgehog antagonism is impaired and proliferation of granule cells is sustained. Activates the caspase cascade. {ECO:0000269|PubMed:15249678, ECO:0000269|PubMed:20081843, E
Tissue Specificity Higher expression in cerebellum than in whole brain and lower expression in medulloblastoma. {ECO:0000269|PubMed:15249678}.

BTB/POZ domain-containing protein KCTD11 (KCTD11), Human, ELISA Kit - E01B0926 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t
Sensitivity 0.1ng/ml
Range 0.5-10ng/ml

BTB/POZ domain containing protein KCTD11 (KCTD11), ELISA Kit - MBS7203607 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BTB/POZ domain-containing protein KCTD11 (KCTD11), ELISA Kit - MBS7204111 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BTB/POZ domain-containing protein KCTD11 (KCTD11), ELISA Kit - MBS7207952 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BTB/POZ domain-containing protein KCTD11 (KCTD11), ELISA Kit - MBS7235619 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BTB/POZ domain-containing protein KCTD11 (KCTD11), ELISA Kit - MBS7237685 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BTB/POZ domain-containing protein KCTD11 (KCTD11), ELISA Kit - MBS7249990 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BTB/POZ domain-containing protein KCTD11 (KCTD11), ELISA Kit - MBS7250074 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BTB/POZ domain-containing protein KCTD11 (KCTD11), ELISA Kit - MBS7222695 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BTB/POZ domain-containing protein KCTD11 (KCTD11), ELISA Kit - MBS7247285 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BTB/POZ domain-containing protein KCTD11 (KCTD11), ELISA Kit - MBS7200951 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BTB/POZ domain-containing protein KCTD11 (KCTD11), ELISA Kit - MBS7222523 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BTB/POZ domain-containing protein KCTD11 (KCTD11), ELISA Kit - MBS7247101 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human KCTD11 ELISA Kit - E005390 from Biobool

Category ELISA Kit
Search more