S1PR5

Gene Symbol	S1PR5
Entrez Gene	53637
Alt Symbol	EDG8, Edg-8, S1P5, SPPR-1, SPPR-2
Species	Human
Gene Type	protein-coding
Description	sphingosine-1-phosphate receptor 5
Other Description	S1P receptor 5|S1P receptor Edg-8|endothelial differentiation G-protein-coupled receptor 8|endothelial differentiation, sphingolipid G-protein-coupled receptor, 8|sphingosine 1-phosphate receptor 5|sphingosine 1-phosphate receptor EDG8|sphingosine 1-phosphate receptor Edg-8
Swissprots	Q6NW11 Q9H228
Accessions	AAG38113 AAP20653 BAB89315 CAF85890 EAW84113 EAW84114 EAW84115 Q9H228 AF088014 AF331840 AAL57041 AF331841 AAL57042 AF331842 AAL57043 AK074661 BAC11119 AK094880 BC034703 AAH34703 BC067781 AAH67781 DA747912 DA866378 DB013424 DQ891290 ABM82216 DQ893341 ABM84267 DQ894474 ABM85400 DQ896661 ABM87660 NM_001166215 NP_001159687 NM_030760 NP_110387
Function	Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells. {ECO:0000250}.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Widely expressed in the brain, most prominently in the corpus callosum, which is predominantly white matter. Detected in spleen, peripheral blood leukocytes, placenta, lung, aorta and fetal spleen. Low-level signal detected in many tissue extracts. Overexpressed in leukemic large granular lymphocytes. Isoform 1 is predominantly expressed in peripheral tissues. Isoform 2 is expressed in brain, spleen and peripheral blood leukocytes. {ECO:0000269|PubMed:11705398, ECO:0000269|PubMed:12234605, ECO:0000269|PubMed:12427546}.
Top Pathways	Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat S1PR5 / EDG8 / S1P5 ELISA Kit (Sandwich ELISA) - LS-F12548 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Sphingosine 1-phosphate receptor 5, S1PR5, Human, ELISA Kit - E0328h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 78-5000 pg/mL

S1PR5, ELISA Kit - MBS2515831 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 46.875pg/mL Range 78.125-5000pg/mL

Sphingosine 1 Phosphate Receptor 5 (S1PR5), ELISA Kit - MBS2024703 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.059ng/mL. Range 0.156-10ng/mL

sphingosine-1-phosphate receptor 5, ELISA Kit - MBS9331118 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml. Range 0.25 ng/ml - 8 ng/ml.

ELISA Kit for Sphingosine 1 Phosphate Receptor 5 (S1PR5) - SEE695Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.059ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Mouse S1PR5 / EDG8 / S1P5 ELISA Kit (Custom ELISA) - LS-F14313 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Human S1PR5 / EDG8 / S1P5 ELISA Kit (Custom ELISA) - LS-F14311 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Pig S1PR5 / EDG8 / S1P5 ELISA Kit (Custom ELISA) - LS-F14312 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Human Sphingosine 1-phosphate receptor 5 ELISA Kit - abx253807 from Abbexa Category ELISA Kit Range 78 pg/ml - 5000 pg/ml

Mouse S1PR5 / EDG8 / S1P5 ELISA Kit (Sandwich ELISA) - LS-F24063 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 46.875 pg/ml Range 0.156-10 ng/ml

Mouse S1PR5 / EDG8 / S1P5 ELISA Kit (Sandwich ELISA) - LS-F25473 from LifeSpan Bioscience Category ELISA Kit Prices $800.00 Sizes 1 plate Sensitivity 0.059 ng/ml Range 0.156-10 ng/ml

Human Sphingosine 1-phosphate receptor 5 ELISA Kit - EKE51765 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 30 pg/mL Range 78-5000 pg/mL

S1PR5 - EKH1702 from Nordic BioSite Sensitivity 46.9pg/ml Range 78-5000pg/ml

Human S1PR5 ELISA Kit - E036446 from Biobool Category ELISA Kit Sensitivity <46.9pg/ml

S1PR5 ELISA Kit (Human) (OKEH04293) - OKEH04293 from Aviva Systems Biology Category ELISA Kit Prices $596.00 Sizes 96 wells Sensitivity < 39 pg/mL Range 78 - 5,000 pg/mL

Sphingosine 1 Phosphate Receptor 5 (S1PR5), ELISA Kit - MBS9359889 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sphingosine 1 Phosphate Receptor 5 (S1PR5), ELISA Kit - MBS9364519 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sphingosine 1 Phosphate Receptor 5 (S1PR5), ELISA Kit - MBS9350608 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sphingosine 1 Phosphate Receptor 5 (S1PR5), ELISA Kit - MBS9349845 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sphingosine 1 Phosphate Receptor 5 (S1PR5), ELISA Kit - MBS9360655 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sphingosine 1 Phosphate Receptor 5 (S1PR5), ELISA Kit - MBS9370111 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sphingosine 1 Phosphate Receptor 5 (S1PR5), ELISA Kit - MBS9357276 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sphingosine 1 Phosphate Receptor 5 (S1PR5), ELISA Kit - MBS9367996 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sphingosine 1 Phosphate Receptor 5 (S1PR5), ELISA Kit - MBS9353609 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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