CCNF

Gene Symbol CCNF
Entrez Gene 899
Alt Symbol FBX1, FBXO1
Species Human
Gene Type protein-coding
Description cyclin F
Other Description F-box only protein 1|G2/mitotic-specific cyclin-F|cyclin-F
Swissprots P41002 Q96EG9 B2R8H3
Accessions EAW85510 P41002 AB208829 BAD92066 AK313371 BAG36170 BC012349 AAH12349 DA960397 DB523776 DQ890775 ABM81701 U17105 AAB60342 Z36714 CAA85308 NM_001761 NP_001752
Function Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication. {ECO:0000269|PubMed:20596027}.
Subcellular Location Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localization in the centrosome is rare in S phase cells and increases in G2 cells, Localizes on both the mother and daughter centrioles. Localization to centrosomes is not dependent on CP110. Also localizes to the nucleus.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:7813445}.

cyclin F (C-20) - sc-952 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
cyclin F (C-20): sc-952. Western blot analysis of cyclin F expression in A-431 whole cell lysate.

cyclin F (N-20) - sc-953 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
cyclin F (N-20): sc-953. Western blot analysis of cyclin F expression in Ramos nuclear extract.

cyclin F (H-300) - sc-13009 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
cyclin F (H-300): sc-13009. Western blot analysis of cyclin F expression in Ramos nuclear extract.

cyclin F (2123D1a) - sc-81242 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
cyclin F (2123D1a): sc-81242 Western Blot analysis of human recombinant cyclin F fusion protein.

Anti-Cyclin F antibody - ab203117 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin/PFA-fixed paraffin-embedded rat brain tissue sections labeling Cyclin F with ab203117 at a 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

Anti-Cyclin F antibody - ab173922 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-Cyclin F antibody (ab173922) at 1/100 dilution + Mouse liver tissue lysate at 35 µg

Anti-Cyclin F antibody - ab180720 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cyclin F antibody (ab180720) at 1/500 dilutionLane 1 : HeLa cell line lysateLane 2 : Huvec cell line extract

Anti-Cyclin F antibody - ab53055 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cyclin F antibody (ab53055) at 1/500 dilutionLane 1 : extracts from HeLa cells, no immunising peptideLane 2 : extracts from HeLa cells, immunising peptide present

Anti-Cyclin F antibody - ab123601 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cyclin F antibody (ab123601) at 0.1 µg/mlLane 1 : Whole cell lysate from HeLa cells at 50 µgLane 2 : Whole cell lysate from HeLa cells at 15 µgLane 3 : Whole cell lysate from 293T cells at 50 µgLane 4 : Whole cell lysate from Jurkat cells at 50 µgdeveloped using the ECL technique

Anti-Cyclin F antibody - ab137450 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Cyclin F antibody (ab137450) at 1/1000 dilution + HeLaS3 whole cell lysate at 30 µg

Anti-Cyclin F antibody [2123D1a] - ab50811 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2123D1a

Anti-CCNF / Cyclin F Antibody - LS-C64120 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-CCNF / Cyclin F Antibody (clone 2123D1a) - LS-C184400 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2123D1a

Anti-CCNF / Cyclin F Antibody (aa496-524, AP) - LS-C213150 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNF / Cyclin F Antibody (aa496-524, APC) - LS-C213152 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNF / Cyclin F Antibody (aa496-524, Biotin) - LS-C213153 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNF / Cyclin F Antibody (aa496-524, FITC) - LS-C213154 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNF / Cyclin F Antibody (aa496-524, Azide-free, HRP) - LS-C213155 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNF / Cyclin F Antibody (aa495-524) - LS-C320117 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNF / Cyclin F Antibody (aa496-524, PE) - LS-C213156 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNF / Cyclin F Antibody (aa736-786) - LS-C290085 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human Cyclin F by Western Blot. Samples: Whole cell lysate from HeLa (15 and 50 ug), 293T (T; 50 ug) and Jurkat (J; 50 ug) cells. Antibody: Affinity purified rabbit anti-Cyclin F antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Anti-CCNF / Cyclin F Antibody (aa737-786) - LS-C118426 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HeLa cells, using Cyclin F Antibody. The lane on the right is treated with the synthesized peptide.

Anti-CCNF / Cyclin F Antibody (clone 2123D1a) - LS-C342446 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2123D1a
Western blot analysis of immunized recombinant protein, using anti-CCNF monoclonal antibody.

Anti-CCNF / Cyclin F Antibody (Ile772) - LS-C175987 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of Cyclin F (I772) pAb in paraffin-embedded human breast carcinoma tissue.

Anti-CCNF / Cyclin F Antibody (aa496-524) - LS-C159294 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CCNF Antibody western blot of mouse liver tissue lysates (35 ug/lane). The CCNF Antibody detected the CCNF protein (arrow).
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