CCNF

Gene Symbol CCNF
Entrez Gene 899
Alt Symbol FBX1, FBXO1
Species Human
Gene Type protein-coding
Description cyclin F
Other Description F-box only protein 1|G2/mitotic-specific cyclin-F|cyclin-F
Swissprots P41002 Q96EG9 B2R8H3
Accessions EAW85510 P41002 AB208829 BAD92066 AK313371 BAG36170 BC012349 AAH12349 DA960397 DB523776 DQ890775 ABM81701 U17105 AAB60342 Z36714 CAA85308 NM_001761 NP_001752
Function Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication. {ECO:0000269|PubMed:20596027}.
Subcellular Location Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localization in the centrosome is rare in S phase cells and increases in G2 cells, Localizes on both the mother and daughter centrioles. Localization to centrosomes is not dependent on CP110. Also localizes to the nucleus.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:7813445}.

cyclin F CRISPR/Cas9 KO Plasmid (h) - sc-401505 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cyclin F HDR Plasmid (h) - sc-401505-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cyclin F Double Nickase Plasmid (h) - sc-401505-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cyclin F Double Nickase Plasmid (h2) - sc-401505-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cyclin F CRISPR Activation Plasmid (h) - sc-401505-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cyclin F CRISPR Activation Plasmid (h2) - sc-401505-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cyclin F Lentiviral Activation Particles (h) - sc-401505-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cyclin F Lentiviral Activation Particles (h2) - sc-401505-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cyclin F siRNA (h) - sc-35138 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

cyclin F shRNA Plasmid (h) - sc-35138-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

cyclin F shRNA (h) Lentiviral Particles - sc-35138-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU153851 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5637 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12774 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr12774

CCNF siRNA (Human) - CRH0631 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CCNF - MBS8211718 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CCNF (NM_001761.2) - SHH257905 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CCNF(NM_001761.2) - SHG152425 from Creative biogene

Category siRNA
Species Reactivities Human

Human CCNF siRNA - orb261133 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CCNF shRNA Plasmid (Human) - CHH0631 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CCNF miRNA 3'UTR clone - MiUTR1H-01818 from Creative biogene

Species Reactivities Human
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