CCNF

Gene Symbol	CCNF
Entrez Gene	899
Alt Symbol	FBX1, FBXO1
Species	Human
Gene Type	protein-coding
Description	cyclin F
Other Description	F-box only protein 1|G2/mitotic-specific cyclin-F|cyclin-F
Swissprots	P41002 Q96EG9 B2R8H3
Accessions	EAW85510 P41002 AB208829 BAD92066 AK313371 BAG36170 BC012349 AAH12349 DA960397 DB523776 DQ890775 ABM81701 U17105 AAB60342 Z36714 CAA85308 NM_001761 NP_001752
Function	Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication. {ECO:0000269|PubMed:20596027}.
Subcellular Location	Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localization in the centrosome is rare in S phase cells and increases in G2 cells, Localizes on both the mother and daughter centrioles. Localization to centrosomes is not dependent on CP110. Also localizes to the nucleus.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:7813445}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Cyclin F full length protein - ab158044 from Abcam Category Protein Source Wheat germ Species Human

CCNF / Cyclin F Antibody Blocking Peptide - LS-E5782 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Cyclin F Protein - H00000899-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CCNF-Antibody-Center-Blocking-Peptide - BP18322c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Cyclin F Blocking Peptide - abx062366 from Abbexa Category Peptide Species Human, Mouse, Rat

Cyclin F - H00000899-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Cyclin F - H00000899-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CCNF fusion protein - ag9322 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

CCNF fusion protein - ag9207 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Cyclin F Blocking Peptide - CBP1172 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

Cyclin F (I772) Peptide - BS1087P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Cyclin-F(CCNF) - CSB-YP004819HU CSB-EP004819HU CSB-BP004819HU CSB-MP004819HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CCNF Peptide, Human - M34GP02652H from Creative Peptides Category Peptide Source Synthetic. Species Human

Cyclin F Recombinant Protein Antigen - NBP2-57349PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Cyclin F Recombinant Protein Antigen - NBP2-57569PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Cyclin-F (CCNF), Recombinant Protein - MBS717493 from MyBioSource Category Protein Prices $1,605.00, $1,605.00, $1,830.00, $1,830.00, $2,755.00, $2,755.00, $3,215.00, $3,215.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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