OSGEP

Gene Symbol OSGEP
Entrez Gene 55644
Alt Symbol GCPL1, KAE1, OSGEP1, PRSMG1
Species Human
Gene Type protein-coding
Description O-sialoglycoprotein endopeptidase
Other Description N6-L-threonylcarbamoyladenine synthase|hOSGEP|probable O-sialoglycoprotein endopeptidase|probable tRNA N6-adenosine threonylcarbamoyltransferase|probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP|t(6)A synthase|t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP|tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP
Swissprots Q6IAC3 Q9NPF4
Accessions BAB33147 EAW66469 EAW66470 Q9NPF4 AB050442 BAB33172 AF052137 AJ271669 CAB71031 AK000418 BAA91150 AK054823 AK055492 BC032310 AAH32310 BX428958 CD365329 CR457232 CAG33513 DA068526 DQ894806 ABM85732 EU176277 ABW03728 XM_011536930 XP_011535232 XM_011536931 XP_011535233 XM_011536932 XP_011535234 NM_017807 NP_060277
Function Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. {ECO:0000255|HAMAP-Rule:MF_03180}.
Subcellular Location Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03180}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03180, ECO:0000269|PubMed:22912744}.
Tissue Specificity Widely expressed at low level. Expressed in heart, placenta, liver, kidney, lung, brain, skeletal muscle and pancreas. {ECO:0000269|PubMed:12039036}.

Human OSGEP full length protein - ab132776 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab132776 stained with Coomassie Blue.

Human OSGEP full length protein - ab183238 from Abcam

Category Protein
Source E. coli
Species Human
15% SDS-PAGE analysis of ab183238 (3µg)

Human OSGEP protein fragment - ab127148 from Abcam

Category Protein
Source E. coli
Species Human

OSGEP Antibody Blocking Peptide - LS-E20794 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

OSGEP Antibody Blocking Peptide - LS-E20793 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

OSGEP Recombinant Protein - H00055644-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

OSGEP Blocking Peptide - 33R-7254 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

OSGEP Blocking Peptide - 33R-2460 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

OSGEP protein (His tag) - 80R-3926 from Fitzgerald

Category Protein
Prices $275.00
Sizes 100 µg
Source E.coli

OSGEP / GCPL1 (His-tag) - AR51613PU-N from Acris Antibodies

Category Protein
Prices $790.00
Sizes 500 µg
Source E. coli
Species Human
OSGEP / GCPL1

OSGEP / GCPL1 (His-tag) - AR51613PU-S from Acris Antibodies

Category Protein
Prices $340.00
Sizes 100 µg
Source E. coli
Species Human
OSGEP / GCPL1

OSGEP / GCPL1 - H00055644-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

OSGEP / GCPL1 - H00055644-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

OSGEP fusion protein - ag4308 from Proteintech Group

Category Protein
Source E. coli-derived, T-HIS
Species Human

Recombinant Human Probable tRNA threonylcarbamoyladenosine biosynthesis protein - CSB-YP878842HU CSB-EP878842HU CSB-BP878842HU CSB-MP878842HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

OSGEP, 1- 335aa, Human, His tag, E.coli (Denatured) - ATGP2793 from ATGen

Category Protein
Prices $80.00, $240.00, $720.00
Sizes 20 µg, 100 µg, 500 µg
Species Human
SDSPAGE

OSGEP Protein - abx164377 from Abbexa

Category Protein
Species Human, Mouse, Rat

OSGEP / GCPL1 - TP307089 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
OSGEP / GCPL1

Probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP (OSGEP), Recombinant Protein - MBS1376928 from MyBioSource

Category Protein
Prices $1,100.00, $1,100.00, $1,325.00, $1,325.00, $1,730.00, $1,730.00, $2,195.00, $2,195.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

OSGEP Recombinant Protein Antigen - NBP1-83378PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

OSGEP-Antibody-C-term-Blocking-peptide - BP5329b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

OSGEP Peptide, Human - M34GP11143H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Recombinant Human OSGEP Protein - NBP2-51805 from Novus Biologicals

Category Protein
Prices $259.00, $759.00
Sizes 100 µg, 500 µg
Source E. coli
Species Human
SDS-Page: OSGEP Recombinant Protein [NBP2-51805] - 15% SDS Page (3 ug)

O-Sialoglycoprotein Endopeptidase, Human Recombinant - 228-20766-1 from RayBiotech

Category Protein
Prices $118.00
Sizes 1 µg
Species Human
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