OSGEP

Gene Symbol OSGEP
Entrez Gene 55644
Alt Symbol GCPL1, KAE1, OSGEP1, PRSMG1
Species Human
Gene Type protein-coding
Description O-sialoglycoprotein endopeptidase
Other Description N6-L-threonylcarbamoyladenine synthase|hOSGEP|probable O-sialoglycoprotein endopeptidase|probable tRNA N6-adenosine threonylcarbamoyltransferase|probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP|t(6)A synthase|t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP|tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP
Swissprots Q6IAC3 Q9NPF4
Accessions BAB33147 EAW66469 EAW66470 Q9NPF4 AB050442 BAB33172 AF052137 AJ271669 CAB71031 AK000418 BAA91150 AK054823 AK055492 BC032310 AAH32310 BX428958 CD365329 CR457232 CAG33513 DA068526 DQ894806 ABM85732 EU176277 ABW03728 XM_011536930 XP_011535232 XM_011536931 XP_011535233 XM_011536932 XP_011535234 NM_017807 NP_060277
Function Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. {ECO:0000255|HAMAP-Rule:MF_03180}.
Subcellular Location Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03180}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03180, ECO:0000269|PubMed:22912744}.
Tissue Specificity Widely expressed at low level. Expressed in heart, placenta, liver, kidney, lung, brain, skeletal muscle and pancreas. {ECO:0000269|PubMed:12039036}.

Osgep CRISPR/Cas9 KO Plasmid (h) - sc-410671 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Osgep HDR Plasmid (h) - sc-410671-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Osgep Double Nickase Plasmid (h) - sc-410671-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Osgep Double Nickase Plasmid (h2) - sc-410671-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Osgep CRISPR Activation Plasmid (h) - sc-410671-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Osgep CRISPR Activation Plasmid (h2) - sc-410671-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Osgep Lentiviral Activation Particles (h) - sc-410671-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Osgep Lentiviral Activation Particles (h2) - sc-410671-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Osgep siRNA (h) - sc-92142 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Osgep shRNA Plasmid (h) - sc-92142-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Osgep shRNA (h) Lentiviral Particles - sc-92142-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

OSGEP RNAi - H00055644-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU007871 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16169 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16169 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00358 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00358

OSGEP siRNA (Human) - CRJ0799 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

OSGEP shRNA Plasmid (Human) - CHJ0799 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

OSGEP miRNA 3'UTR clone - MiUTR3H-11033 from Creative biogene

Species Reactivities Human
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