IZUMO1R

Gene Symbol IZUMO1R
Entrez Gene 390243
Alt Symbol FOLR4, Folbp3, JUNO
Species Human
Gene Type protein-coding
Description IZUMO1 receptor, JUNO
Other Description FR-delta|IZUMO1 receptor protein JUNO|folate receptor 4 (delta) homolog|folate receptor 4, delta (putative)|folate receptor delta|probable folate receptor delta|sperm-egg fusion protein Juno
Swissprots A6ND01
Accessions A6ND01 XM_011542811 XP_011541113 XM_011542812 XP_011541114 NM_001080486 NM_001199206 NP_001186135
Function Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand- receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}. Note=GPI-anchored at the oolemma. {ECO:0000250}.
Top Pathways Endocytosis

Anti-Folate Receptor 4 antibody - ab108067 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-Folate Receptor 4 antibody (ab108067) at 1 µg/ml + MCF7 cell lysate at 10 µg

Anti-Folate Receptor 4 antibody - N-terminal - ab170535 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Folate Receptor 4 antibody - N-terminal (ab170535) at 1/100 dilution + 293 cell line lysate at 35 µgdeveloped using the ECL technique

Anti-IZUMO1R / FOLR4 Antibody (aa20-100) - LS-C129135 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-IZUMO1R / FOLR4 Antibody - LS-C143839 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rat
Clonality Monoclonal

Anti-IZUMO1R / FOLR4 Antibody - LS-C143838 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-IZUMO1R / FOLR4 Antibody (FITC) - LS-C143841 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rat
Clonality Monoclonal

Anti-IZUMO1R / FOLR4 Antibody (APC) - LS-C143845 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rat
Clonality Monoclonal

Anti-IZUMO1R / FOLR4 Antibody (PE) - LS-C143842 from LifeSpan Bioscience

Prices $415.00
Sizes 50 µg
Host Rat
Clonality Monoclonal

Anti-IZUMO1R / FOLR4 Antibody (APC) - LS-C143840 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rat
Clonality Monoclonal

Anti-IZUMO1R / FOLR4 Antibody - LS-C143844 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rat
Clonality Monoclonal

Anti-IZUMO1R / FOLR4 Antibody (Low Endotoxin) - LS-C143843 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rat
Clonality Monoclonal

Anti-IZUMO1R / FOLR4 Antibody (aa148-197) - LS-C116873 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
FOLR4 antibody LS-C116873 Western blot of MCF7 cell lysate.

Anti-IZUMO1R / FOLR4 Antibody (clone TH6, APC) - LS-C147997 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone TH6

Anti-IZUMO1R / FOLR4 Antibody (clone 12A5, Azide-free) - LS-C148004 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone 12A5

Anti-IZUMO1R / FOLR4 Antibody (clone TH6, FITC) - LS-C148383 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone TH6

Anti-IZUMO1R / FOLR4 Antibody (clone TH6, Azide-free) - LS-C148386 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone TH6

Anti-IZUMO1R / FOLR4 Antibody (clone TH6, PE) - LS-C148385 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone TH6

Anti-IZUMO1R / FOLR4 Antibody (aa17-46, APC) - LS-C235342 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IZUMO1R / FOLR4 Antibody (aa17-46, Biotin) - LS-C235343 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IZUMO1R / FOLR4 Antibody (aa17-46, AP) - LS-C235341 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IZUMO1R / FOLR4 Antibody (aa17-46, FITC) - LS-C235344 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IZUMO1R / FOLR4 Antibody (clone 12A5, APC) - LS-C148006 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone 12A5
Flow cytometry of CD4+CD25+ gated mouse splenocytes using rat IgG2b isotype control (left) and LS-C148006 (clone 12A5) (right) at 0.1 ug/10^6 cells.

Anti-IZUMO1R / FOLR4 Antibody (aa17-46, PE) - LS-C235345 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IZUMO1R / FOLR4 Antibody (clone 12A5) - LS-C147998 from LifeSpan Bioscience

Prices $315.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone 12A5
Flow cytometry of CD4+CD25+ gated mouse splenocytes using A) rat IgG2b isotype control and B) LS-C147998 (clone 12A5) at 0.06 ug/10^6 cells.

Anti-IZUMO1R / FOLR4 Antibody (aa56-234, Biotin) - LS-C300718 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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