IZUMO1R

Gene Symbol IZUMO1R
Entrez Gene 390243
Alt Symbol FOLR4, Folbp3, JUNO
Species Human
Gene Type protein-coding
Description IZUMO1 receptor, JUNO
Other Description FR-delta|IZUMO1 receptor protein JUNO|folate receptor 4 (delta) homolog|folate receptor 4, delta (putative)|folate receptor delta|probable folate receptor delta|sperm-egg fusion protein Juno
Swissprots A6ND01
Accessions A6ND01 XM_011542811 XP_011541113 XM_011542812 XP_011541114 NM_001080486 NM_001199206 NP_001186135
Function Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand- receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}. Note=GPI-anchored at the oolemma. {ECO:0000250}.
Top Pathways Endocytosis

IZUMO1R / FOLR4 Antibody Blocking Peptide - LS-E1350 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

IZUMO1R / FOLR4 Antibody Blocking Peptide - LS-E21623 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

FOLR4-Antibody-N-term-Blocking-peptide - BP11990a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Folate Receptor 4 (FOLR4) - RPS334Mu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Human Probable folate receptor delta(FOLR4) - CSB-YP008789HU CSB-EP008789HU CSB-BP008789HU CSB-MP008789HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Probable folate receptor delta (FOLR4), Recombinant Protein - MBS1015644 from MyBioSource

Category Protein
Prices $985.00, $985.00, $1,210.00, $1,210.00, $1,485.00, $1,485.00, $1,950.00, $1,950.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

FOLR4 Peptide, Human - M34GP05829H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Recombinant Human Sperm-egg fusion protein Juno(IZUMO1R) - AP73989 from Signalway Antibody

Category Protein
Prices $105.00, $260.00, $454.00, $735.00, $1,240.00, $1,980.00
Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg
Source E.coli
Species Human

Sperm-egg fusion protein Juno, Recombinant Protein - MBS9423569 from MyBioSource

Category Protein
Prices $165.00, $280.00, $435.00, $665.00, $1,080.00
Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg
Source E Coli
Species Human

IZUMO1R Recombinant Protein (Human) (OPCA04382) - OPCA04382 from Aviva Systems Biology

Category Protein
Species Human

Human IZUMO1R protein - orb383189 from Biorbyt

Category Protein
Species Human
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