PLG

Gene Symbol	PLG
Entrez Gene	5340
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	plasminogen
Other Description	plasmin
Swissprots	Q6PA00 P00747 Q5TEH4 Q15146
Accessions	AAA60113 AAA60123 AAN85555 CBY88485 EAW47591 EAW47592 P00747 AK298338 BAG60586 AK308036 AK312966 BAG35805 BC060513 AAH60513 BU073846 CR749293 CAH18148 DR004070 K02922 AAA60124 M74220 AAA36451 X05199 CAA28831 NM_000301 NP_000292 NM_001168338 NP_001161810
Function	Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. {ECO:0000269|PubMed:14699093}.
Subcellular Location	Secreted {ECO:0000269|PubMed:10077593, ECO:0000269|PubMed:14699093}. Note=Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface.
Tissue Specificity	Present in plasma and many other extracellular fluids. It is synthesized in the liver.
Top Pathways	Complement and coagulation cascades, Staphylococcus aureus infection, Influenza A, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Plasminogen (PLG) Human SimpleStep ELISA™ Kit - ab196262 from Abcam Category ELISA Kit Prices $484.00 Sizes 1 x 96 tests Sensitivity 0.165 ng/ml Range 0.468 ng/ml - 30 ng/ml

Plasminogen (PLG) Human ELISA Kit - ab108893 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity = 1 ng/ml Range 1.25 ng/ml - 80 ng/ml

Human PLG / Plasmin / Plasminogen ELISA Kit (Sandwich ELISA) - LS-F2748 from LifeSpan Bioscience Category ELISA Kit Prices $610.00 Sizes 1 plate Sensitivity 156 pg/ml Range 156-10000 pg/ml

Human PLG / Plasmin / Plasminogen ELISA Kit (Sandwich ELISA) - LS-F4495 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 0.313 ng/ml Range 156-10000 pg/ml

Rat PLG / Plasmin / Plasminogen ELISA Kit (Sandwich ELISA) - LS-F4994 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 6.7 ng/ml Range 156-10000 pg/ml

Human PLG / Plasmin / Plasminogen ELISA Kit (Sandwich ELISA) - LS-F10425 from LifeSpan Bioscience Category ELISA Kit Prices $330.00 Sizes 1 plate Sensitivity 0.11 ng/ml Range 156-10000 pg/ml

Mouse PLG / Plasmin / Plasminogen ELISA Kit (Sandwich ELISA) - LS-F10445 from LifeSpan Bioscience Category ELISA Kit Prices $440.00 Sizes 1 plate Sensitivity 0.49 ng/ml Range 156-10000 pg/ml

Rat PLG / Plasmin / Plasminogen ELISA Kit (Sandwich ELISA) - LS-F12350 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 7.8 Range 156-10000 pg/ml

Pig PLG / Plasmin / Plasminogen ELISA Kit (Sandwich ELISA) - LS-F12349 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 1.56 Range 156-10000 pg/ml

Human Angiostatin ELISA Kit - RAB0407 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

Plasmin/Antiplasmin Complex (PAP) BioAssay™ ELISA Kit (Human) - 027466 from USBiological Life Science Category ELISA Kit Sensitivity 3.5pg/ml Range 7.8-500pg/ml

Plasmin/Antiplasmin Complex (PAP) BioAssay™ ELISA Kit (Human) - 201510 from USBiological Life Science Category ELISA Kit Sensitivity 0.1ng/mL Range 0.5-10ng/mL

Murine Plasminogen Antibody Pair - 55R-1014 from Fitzgerald Category Antibody Pair Prices $465.00 Sizes 4 plates

Plasminogen Antibody Pair - 55R-1013 from Fitzgerald Category Antibody Pair Prices $465.00 Sizes 5 plates

Plasminogen ELISA kit - 55R-1883 from Fitzgerald Category ELISA Kit Prices $495.00 Sizes 1 kit

Human Plasmin/Fibrinolysin ELISA Kit - abx052952 from Abbexa Category ELISA Kit

Human Plasminogen ELISA Kit - abx051854 from Abbexa Category ELISA Kit

Human Plasminogen ELISA Kit - abx152771 from Abbexa Category ELISA Kit Sensitivity 0.73 ng/ml Range 1.563 ng/ml - 100 ng/ml

Plasmin, Human, ELISA Kit - E01P0051 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ug/ml Range 0.5-10ug/ml

Plasmin/antiplasmin complex, Human, ELISA Kit - E01P0608 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10 ng/mL,

Plasmin/Fibrinolysin, PL/Fbn, Human, ELISA Kit - YHB2359Hu from ARP American Research Products Category ELISA Kit

Plasminogen, Human, ELISA Kit - E01P0127 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0ng/ml Range 25-500ng/ml

Plasminogen, Plg, Human, ELISA Kit - CSB-E09177h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 3.9 ng/ml Range 15.63 ng/ml -1000 ng/ml

Plasminogen, PLG, Human, ELISA Kit - E1236h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 3.12-200 ng/mL

Plasminogen, Plg, Human, ELISA Kit - E-EL-H2102 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.469 Range 0.781-50ng/mL

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