HRH3

Gene Symbol	HRH3
Entrez Gene	11255
Alt Symbol	GPCR97, HH3R
Species	Human
Gene Type	protein-coding
Description	histamine receptor H3
Other Description	G protein-coupled receptor 97|G-protein coupled receptor 97|H3R|histamine H3 receptor
Swissprots	Q9Y5N1 Q9H4K8 Q9GZX2 Q4QRI7
Accessions	CAC39434 CAC51025 EAW75381 EAW75382 EAW75383 EAW75384 EAW75385 Q9Y5N1 AB019000 BAB17030 AF140538 AAD38151 AF321910 AAL71911 AF321911 AAL71912 AF321912 AAL71913 AF321913 AAL71914 AF346903 AAM43828 AF346904 AAM43829 AF363791 AAK50040 AK074730 BAC11167 BC096840 AAH96840 XM_005260266 XP_005260323 XM_005260267 XP_005260324 NM_007232 NP_009163
Function	The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Expressed predominantly in the CNS, with the greatest expression in the thalamus and caudate nucleus. The various isoforms are mainly coexpressed in brain, but their relative expression level varies in a region-specific manner. Isoform 3 and isoform 7 are highly expressed in the thalamus, caudate nucleus and cerebellum while isoform 5 and isoform 6 show a poor expression. Isoform 5 and isoform 6 show a high expression in the amygdala, substantia nigra, cerebral cortex and hypothalamus. Isoform 7 is not found in hypothalamus or substantia nigra.
Top Pathways	Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat HRH3 / Histamine 3 Receptor ELISA Kit (Sandwich ELISA) - LS-F7900 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.124 ng/ml Range 0.313-20 ng/ml

histamine receptor H3 - MBS9318669 from MyBioSource Category ELISA Kit Prices $435.00, $600.00 Sizes 48 strip wells, 96 strip wells

Histamine Receptor H3, ELISA Kit - MBS056089 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histamine Receptor H3, ELISA Kit - MBS099121 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histamine Receptor H3, ELISA Kit - MBS080705 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histamine Receptor H3, ELISA Kit - MBS055880 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histamine Receptor H3, ELISA Kit - MBS055640 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml. Range 0.625 ng/ml - 20 ng/ml.

Histamine Receptor H3, ELISA Kit - MBS056215 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histamine Receptor H3, ELISA Kit - MBS086961 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histamine Receptor H3 (HRH3), ELISA Kit - MBS2020278 from MyBioSource Category ELISA Kit Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.124ng/mL. Range 0.313-20ng/mL

ELISA Kit for Histamine Receptor H3 (HRH3) - SEG039Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.124ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human HRH3 ELISA Kit - E085762 from Biobool Category ELISA Kit

Histamine H3 receptor, ELISA Kit - MBS284642 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histamine Receptor H3 (HRH3), ELISA Kit - MBS9378570 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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