Gene Symbol | Ccl5 |
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Entrez Gene | 81780 |
Alt Symbol | Rantes, Scya5 |
Species | Rat |
Gene Type | protein-coding |
Description | chemokine (C-C motif) ligand 5 |
Other Description | C-C motif chemokine 5|SIS-delta|T-cell-specific protein RANTES|regulated upon activation normal T-cell expressed and secreted|small inducible cytokine A5|small-inducible cytokine A5 |
Swissprots | P50231 |
Accessions | EDM05488 P50231 BC058138 AAH58138 BP467039 EF121972 ABL63411 EF122007 ABL63446 U06436 AAA96499 NM_031116 NP_112378 |
Function | Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. {ECO:0000250|UniProtKB:P13501}. |
Subcellular Location | Secreted. |
Top Pathways | Chemokine signaling pathway, TNF signaling pathway, Herpes simplex infection, Influenza A, Rheumatoid arthritis |
Anti-RANTES antibody - ab9783 from Abcam
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CCL5/RANTES Antibody - AF1010 from Novus Biologicals
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CCL5/RANTES Antibody [Biotin] - BAF1010 from Novus Biologicals
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RANTES Antibody - abx104740 from Abbexa
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RANTES / CCL5 antibody - PP051B1 from Acris Antibodies
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RANTES / CCL5 antibody - PP051B2 from Acris Antibodies
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RANTES / CCL5 antibody - PP051P1 from Acris Antibodies
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RANTES / CCL5 antibody - PP051P2 from Acris Antibodies
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Rabbit Anti-RANTES Antibody - 168-10909 from RayBiotech
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Rabbit Anti-Rat RANTES / CCL5 [+Biotin] - DS-PB-01719 from RayBiotech
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Rabbit Anti-Rat RANTES / CCL5 - DS-PB-01720 from RayBiotech
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Anti-Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) - 20-2276 from ARP American Research Products
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RANTES Antibody - XP-5258 from ProSci
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RANTES Antibody (biotin) - XP-5258Bt from ProSci
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Anti-CCL5 polyclonal antibody - CPBT-65255RR from Creative Diagnostics
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CCL5 (RANTES) Polyclonal Antibody - PA1-84201 from Thermo Fisher Scientific
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RANTES, Polyclonal Antibody - MBS221287 from MyBioSource
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RANTES, Polyclonal Antibody - MBS695407 from MyBioSource
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RANTES, Polyclonal Antibody - MBS695192 from MyBioSource
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RANTES, Polyclonal Antibody - MBS691396 from MyBioSource
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RANTES, Polyclonal Antibody - MBS220147 from MyBioSource
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RANTES Antibody - AAR18G from AbD Serotec
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Monoclonal Antibody to Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) - MAA116Ra21 from Cloud-clone
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Polyclonal Antibody to Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) - PAA116Ra01 from Cloud-clone
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Biotin-Linked Antibody to Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) - PAA116Ra71 from Cloud-clone
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