Gene Symbol | CAPZB |
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Entrez Gene | 832 |
Alt Symbol | CAPB, CAPPB, CAPZ |
Species | Human |
Gene Type | protein-coding |
Description | capping protein (actin filament) muscle Z-line, beta |
Other Description | F-actin-capping protein subunit beta|capZ beta |
Swissprots | Q8TB49 Q5U0L4 Q32Q68 P47756 Q9NUC4 |
Accessions | EAW94888 EAW94889 EAW94890 EAW94891 P47756 AI799520 AK022336 AK125085 BAG54137 AK126650 AK301442 BAG62968 AK313113 BAG35935 BC008095 AAH08095 BC012305 BC024601 AAH24601 BC069031 BC107752 AAI07753 BC109241 AAI09242 BC109242 AAI09243 BE870234 BQ009850 BQ773230 BT019470 AAV38277 BT019471 AAV38278 BX647941 CB267021 CN273493 EB387955 HY021163 U03271 AAA87395 XM_006710938 XP_006711001 XM_011542228 XP_011540530 XM_011542229 XP_011540531 XM_011542230 XP_011540532 NM_001206540 NP_001193469 NM_001206541 NP_001193470 NM_001282162 NP_001269091 NM_004930 NP_004921 |
Function | F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization. {ECO:0000269|PubMed:21834987}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, myofibril, sarcomere {ECO:0000250}. |
CapZ-β (C-17) - sc-27551 from Santa Cruz Biotechnology
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CapZ-β (H-238) - sc-48752 from Santa Cruz Biotechnology
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CapZ-β (N-17) - sc-27552 from Santa Cruz Biotechnology
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Anti-CAPZB antibody - ab54930 from Abcam
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Anti-CAPZB antibody [1H1] - ab122980 from Abcam
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Anti-CAPZB antibody [EPR10236] - ab175212 from Abcam
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Anti-CAPZB antibody - C-terminal - ab174515 from Abcam
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Anti-CAPZB / CAPZ Beta Antibody (N-Terminus, APC) - LS-C275865 from LifeSpan Bioscience
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Anti-CAPZB / CAPZ Beta Antibody (N-Terminus, AP) - LS-C275863 from LifeSpan Bioscience
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Anti-CAPZB / CAPZ Beta Antibody (N-Terminus, Biotin) - LS-C275866 from LifeSpan Bioscience
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Anti-CAPZB / CAPZ Beta Antibody (N-Terminus, FITC) - LS-C275867 from LifeSpan Bioscience
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Anti-CAPZB / CAPZ Beta Antibody (C-Terminus) - LS-C151344 from LifeSpan Bioscience
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Anti-CAPZB / CAPZ Beta Antibody (N-Terminus, Azide-free, HRP) - LS-C275869 from LifeSpan Bioscience
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Anti-CAPZB / CAPZ Beta Antibody (N-Terminus) - LS-C327005 from LifeSpan Bioscience
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Anti-CAPZB / CAPZ Beta Antibody (N-Terminus, PE) - LS-C275868 from LifeSpan Bioscience
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Anti-CAPZB / CAPZ Beta Antibody (aa260-272) - LS-C54606 from LifeSpan Bioscience
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Anti-CAPZB / CAPZ Beta Antibody (N-Terminus) - LS-C346045 from LifeSpan Bioscience
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Anti-CAPZB / CAPZ Beta Antibody (aa229-257) - LS-C168308 from LifeSpan Bioscience
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Anti-CAPZB / CAPZ Beta Antibody (aa54-81) - LS-C168309 from LifeSpan Bioscience
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Anti-CAPZB / CAPZ Beta Antibody (aa1-256) - LS-C185421 from LifeSpan Bioscience
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Anti-CAPZB / CAPZ Beta Antibody (clone 1H1) IHC-plus⢠- LS-B5931 from LifeSpan Bioscience
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CAPZB Antibody - NBP1-85922 from Novus Biologicals
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CAPZB Antibody (1H1) - H00000832-M02 from Novus Biologicals
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CAPZB Antibody (4H8) - H00000832-M03 from Novus Biologicals
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CAPZB Antibody - NB100-814 from Novus Biologicals
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