Gene Symbol | EXTL2 |
---|---|
Entrez Gene | 2135 |
Alt Symbol | EXTR2 |
Species | Human |
Gene Type | protein-coding |
Description | exostosin-like glycosyltransferase 2 |
Other Description | EXT-related protein 2|alpha-1,4-N-acetylhexosaminyltransferase EXTL2|alpha-GalNAcT EXTL2|exostoses (multiple)-like 2|exostosin-like 2|glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase|processed exostosin-like 2 |
Swissprots | D3DT60 B2R795 Q9UBQ6 |
Accessions | EAW72946 EAW72947 EAW72948 Q9UBQ6 AB009284 BAA24081 AF000416 AAC02898 AK001450 AK096914 BAC04893 AK298124 BAG60404 AK312895 BAG35742 AU130571 BC014910 AAH14910 BC036015 AAH36015 BC045681 AAH45681 BP202626 BU689972 BX103291 U76189 AAB93669 XM_005270621 XP_005270678 XM_011540994 XP_011539296 XM_011540995 XP_011539297 XM_011540996 XP_011539298 XM_011540997 XP_011539299 XM_011540998 XP_011539300 NM_001033025 NP_001028197 NM_001261440 NP_001248369 NM_001261441 NP_001248370 NM_001261442 NP_001248371 NM_001439 NP_001430 NR_048570 |
Function | Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N- acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains. {ECO:0000269|PubMed:10318803}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
EXTL2 (C-20) - sc-46952 from Santa Cruz Biotechnology
|
||||||||||
EXTL2 (K-20) - sc-46954 from Santa Cruz Biotechnology
|
||||||||||
Anti-EXTL2 antibody - ab177084 from Abcam
|
||||||||||
Anti-EXTL2 antibody - ab67288 from Abcam
|
||||||||||
Anti-EXTL2 antibody - ab171812 from Abcam
|
||||||||||
Anti-EXTL2 antibody - ab196250 from Abcam
|
||||||||||
Anti-EXTL2 antibody [EPR11130] - ab168391 from Abcam
|
||||||||||
Anti-EXTL2 antibody - C-terminal - ab95211 from Abcam
|
||||||||||
Anti-EXTL2 Antibody (aa269-295) - LS-C167867 from LifeSpan Bioscience
|
||||||||||
Anti-EXTL2 Antibody (aa269-295, APC) - LS-C256888 from LifeSpan Bioscience
|
||||||||||
Anti-EXTL2 Antibody (aa269-295, AP) - LS-C256887 from LifeSpan Bioscience
|
||||||||||
Anti-EXTL2 Antibody (aa269-295, Azide-free, HRP) - LS-C256891 from LifeSpan Bioscience
|
||||||||||
Anti-EXTL2 Antibody (aa269-295, Biotin) - LS-C256889 from LifeSpan Bioscience
|
||||||||||
Anti-EXTL2 Antibody (aa269-295, FITC) - LS-C256890 from LifeSpan Bioscience
|
||||||||||
Anti-EXTL2 Antibody (aa269-295, PE) - LS-C256892 from LifeSpan Bioscience
|
||||||||||
Anti-EXTL2 Antibody - LS-C307956 from LifeSpan Bioscience
|
||||||||||
Anti-EXTL2 Antibody - LS-C310298 from LifeSpan Bioscience
|
||||||||||
Anti-EXTL2 Antibody (aa280-310) - LS-C321231 from LifeSpan Bioscience
|
||||||||||
Anti-EXTL2 Antibody (C-Terminus) - LS-C345434 from LifeSpan Bioscience
|
||||||||||
Exostosin-like 2/EXTL2 Antibody - 30310002 from Novus Biologicals
|
||||||||||
Exostosin-like 2/EXTL2 Antibody - NBP2-16394 from Novus Biologicals
|
||||||||||
Exostosin-like 2/EXTL2 Antibody - H00002135-B01 from Novus Biologicals
|
||||||||||
Exostosin-like 2/EXTL2 Antibody - H00002135-B02 from Novus Biologicals
|
||||||||||
Exostosin-like 2/EXTL2 Antibody - H00002135-B02P from Novus Biologicals
|
||||||||||
Exostosin-like 2/EXTL2 Antibody - H00002135-B01P from Novus Biologicals
|