EXTL2

Gene Symbol EXTL2
Entrez Gene 2135
Alt Symbol EXTR2
Species Human
Gene Type protein-coding
Description exostosin-like glycosyltransferase 2
Other Description EXT-related protein 2|alpha-1,4-N-acetylhexosaminyltransferase EXTL2|alpha-GalNAcT EXTL2|exostoses (multiple)-like 2|exostosin-like 2|glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase|processed exostosin-like 2
Swissprots D3DT60 B2R795 Q9UBQ6
Accessions EAW72946 EAW72947 EAW72948 Q9UBQ6 AB009284 BAA24081 AF000416 AAC02898 AK001450 AK096914 BAC04893 AK298124 BAG60404 AK312895 BAG35742 AU130571 BC014910 AAH14910 BC036015 AAH36015 BC045681 AAH45681 BP202626 BU689972 BX103291 U76189 AAB93669 XM_005270621 XP_005270678 XM_011540994 XP_011539296 XM_011540995 XP_011539297 XM_011540996 XP_011539298 XM_011540997 XP_011539299 XM_011540998 XP_011539300 NM_001033025 NP_001028197 NM_001261440 NP_001248369 NM_001261441 NP_001248370 NM_001261442 NP_001248371 NM_001439 NP_001430 NR_048570
Function Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N- acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains. {ECO:0000269|PubMed:10318803}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Ubiquitous.
Top Pathways Glycosaminoglycan biosynthesis - heparan sulfate / heparin

EXTL2 CRISPR/Cas9 KO Plasmid (h) - sc-416807 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EXTL2 HDR Plasmid (h) - sc-416807-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EXTL2 Double Nickase Plasmid (h) - sc-416807-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EXTL2 Double Nickase Plasmid (h2) - sc-416807-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EXTL2 CRISPR Activation Plasmid (h) - sc-416807-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EXTL2 CRISPR Activation Plasmid (h2) - sc-416807-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EXTL2 Lentiviral Activation Particles (h) - sc-416807-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EXTL2 Lentiviral Activation Particles (h2) - sc-416807-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EXTL2 siRNA (h) - sc-60611 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EXTL2 shRNA Plasmid (h) - sc-60611-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EXTL2 shRNA (h) Lentiviral Particles - sc-60611-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Exostosin-like 2/EXTL2 RNAi - H00002135-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Exostosin-like 2/EXTL2 RNAi - H00002135-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU143061 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8059 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8059 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09859 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09859

EXTL2 siRNA (Human) - CRH1485 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EXTL2 - MBS8217129 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human EXTL2 (NM_001439.3) - SHH288245 from Creative biogene

Category siRNA
Species Reactivities Human

EXTL2 shRNA Plasmid (Human) - CHH1485 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

EXTL2 miRNA 3'UTR clone - MiUTR3H-04952 from Creative biogene

Species Reactivities Human

EXTL2 miRNA 3'UTR clone - MiUTR3H-04953 from Creative biogene

Species Reactivities Human
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