EXTL2

Gene Symbol	EXTL2
Entrez Gene	2135
Alt Symbol	EXTR2
Species	Human
Gene Type	protein-coding
Description	exostosin-like glycosyltransferase 2
Other Description	EXT-related protein 2|alpha-1,4-N-acetylhexosaminyltransferase EXTL2|alpha-GalNAcT EXTL2|exostoses (multiple)-like 2|exostosin-like 2|glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase|processed exostosin-like 2
Swissprots	D3DT60 B2R795 Q9UBQ6
Accessions	EAW72946 EAW72947 EAW72948 Q9UBQ6 AB009284 BAA24081 AF000416 AAC02898 AK001450 AK096914 BAC04893 AK298124 BAG60404 AK312895 BAG35742 AU130571 BC014910 AAH14910 BC036015 AAH36015 BC045681 AAH45681 BP202626 BU689972 BX103291 U76189 AAB93669 XM_005270621 XP_005270678 XM_011540994 XP_011539296 XM_011540995 XP_011539297 XM_011540996 XP_011539298 XM_011540997 XP_011539299 XM_011540998 XP_011539300 NM_001033025 NP_001028197 NM_001261440 NP_001248369 NM_001261441 NP_001248370 NM_001261442 NP_001248371 NM_001439 NP_001430 NR_048570
Function	Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N- acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains. {ECO:0000269|PubMed:10318803}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity	Ubiquitous.
Top Pathways	Glycosaminoglycan biosynthesis - heparan sulfate / heparin

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

EXTL2 protein (His-DHFR tag) - ab127444 from Abcam Category Protein Prices $364.00 Sizes 50 µg Source E. coli Species Human

Human EXTL2 protein fragment - ab132728 from Abcam Category Protein Source Wheat germ Species Human

EXTL2 Antibody Blocking Peptide - LS-E10018 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Exostosin-like 2/EXTL2 Protein - H00002135-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

EXTL2-Antibody-C-term-Blocking-Peptide - BP9234b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Exostosin-like 2 - H00002135-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Exostosin-like 2 - H00002135-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

EXTL2 fusion protein - Ag3548 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human EXTL2, GST-tagged - EXTL2-12606H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Exostosin-like 2(EXTL2) - CSB-YP880066HU CSB-EP880066HU CSB-BP880066HU CSB-MP880066HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Exostosin-like 2 (transcript variant 1) - TP307406 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

EXTL2 Peptide, Human - M34GP05154H from Creative Peptides Category Peptide Source Synthetic. Species Human

Exostosin-like 2/EXTL2 Recombinant Protein Antigen - NBP2-56467PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Search more