Gene Symbol | GPAA1 |
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Entrez Gene | 8733 |
Alt Symbol | GAA1, hGAA1 |
Species | Human |
Gene Type | protein-coding |
Description | glycosylphosphatidylinositol anchor attachment 1 |
Other Description | GAA1 protein homolog|GPAA1P anchor attachment protein 1 homolog|GPI anchor attachment protein 1|GPI transamidase subunit|anchor attachment protein 1 (Gaa1p, yeast) homolog|glycophosphatidylinositol anchor attachment 1|glycosylphosphatidylinositol anchor attachment 1 protein|glycosylphosphatidylinositol anchor attachment protein 1 homolog |
Swissprots | Q9UQ31 O43292 Q9NSS0 |
Accessions | BAA82587 BAA82590 CAH05399 EAW82161 EAW82162 EAW82163 EAW82164 EAW82165 O43292 AB002135 BAA82588 AB006969 BAA24035 AK312759 BAG35625 AL157437 CAB75660 BC003171 AAH03171 BC004129 AAH04129 BC006383 AAH06383 DQ895039 ABM85965 EU176312 ABW03763 NM_003801 NP_003792 |
Function | Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate. {ECO:0000269|PubMed:9468317}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:11483512}; Multi-pass membrane protein {ECO:0000269|PubMed:11483512}. |
Tissue Specificity | Ubiquitously expressed in fetal and adult tissues. Expressed at higher levels in fetal tissues than adult tissues. {ECO:0000269|PubMed:9468317}. |
Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
Human GPAA1 full length protein - ab160167 from Abcam
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Human GPAA1 protein fragment - ab160168 from Abcam
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GPAA1 Antibody Blocking Peptide - LS-E440 from LifeSpan Bioscience
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GPAA1 Antibody Blocking Peptide - LS-E16902 from LifeSpan Bioscience
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Recombinant Human GPAA1 Protein - H00008733-P01 from Novus Biologicals
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GPAA1 Partial Recombinant Protein - H00008733-Q01 from Novus Biologicals
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GPAA1-Antibody-N-term-Blocking-peptide - BP10722a from Abgent, a WuXi AppTec company
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GPAA1 Blocking Peptide - 33R-4996 from Fitzgerald
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GPAA1 / GAA1 - H00008733-P01-10 from Acris Antibodies
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GPAA1 / GAA1 - H00008733-P01-25 from Acris Antibodies
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GPAA1 / GAA1 - H00008733-Q01-10 from Acris Antibodies
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GPAA1 / GAA1 - H00008733-Q01-25 from Acris Antibodies
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GPAA1 fusion protein - Ag0152 from Proteintech Group
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Recombinant Human GPAA1, GST-tagged - GPAA1-13405H from Creative Biomart
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GPAA1 Peptide, Human - M34GP06471H from Creative Peptides
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Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1), Recombinant Protein - MBS7015978 from MyBioSource
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Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1), Recombinant Protein - MBS1065282 from MyBioSource
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