Gene Symbol | GPAA1 |
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Entrez Gene | 8733 |
Alt Symbol | GAA1, hGAA1 |
Species | Human |
Gene Type | protein-coding |
Description | glycosylphosphatidylinositol anchor attachment 1 |
Other Description | GAA1 protein homolog|GPAA1P anchor attachment protein 1 homolog|GPI anchor attachment protein 1|GPI transamidase subunit|anchor attachment protein 1 (Gaa1p, yeast) homolog|glycophosphatidylinositol anchor attachment 1|glycosylphosphatidylinositol anchor attachment 1 protein|glycosylphosphatidylinositol anchor attachment protein 1 homolog |
Swissprots | Q9UQ31 O43292 Q9NSS0 |
Accessions | BAA82587 BAA82590 CAH05399 EAW82161 EAW82162 EAW82163 EAW82164 EAW82165 O43292 AB002135 BAA82588 AB006969 BAA24035 AK312759 BAG35625 AL157437 CAB75660 BC003171 AAH03171 BC004129 AAH04129 BC006383 AAH06383 DQ895039 ABM85965 EU176312 ABW03763 NM_003801 NP_003792 |
Function | Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate. {ECO:0000269|PubMed:9468317}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:11483512}; Multi-pass membrane protein {ECO:0000269|PubMed:11483512}. |
Tissue Specificity | Ubiquitously expressed in fetal and adult tissues. Expressed at higher levels in fetal tissues than adult tissues. {ECO:0000269|PubMed:9468317}. |
Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
GPAA1 (F-12) - sc-373710 from Santa Cruz Biotechnology
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GPAA1 (D-15) - sc-49018 from Santa Cruz Biotechnology
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GPAA1 (H-311) - sc-67235 from Santa Cruz Biotechnology
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GPAA1 (C-12) - sc-49017 from Santa Cruz Biotechnology
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Anti-GPAA1 antibody - ab66032 from Abcam
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Anti-GPAA1 antibody - ab126951 from Abcam
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Anti-GPAA1 antibody - ab107499 from Abcam
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Anti-GPAA1 Antibody (aa46-73) - LS-C166593 from LifeSpan Bioscience
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Anti-GPAA1 Antibody (aa46-73, AP) - LS-C257908 from LifeSpan Bioscience
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Anti-GPAA1 Antibody (aa46-73, APC) - LS-C257909 from LifeSpan Bioscience
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Anti-GPAA1 Antibody (aa46-73, Biotin) - LS-C257911 from LifeSpan Bioscience
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Anti-GPAA1 Antibody (aa46-73, FITC) - LS-C257912 from LifeSpan Bioscience
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Anti-GPAA1 Antibody (aa46-73, Azide-free, HRP) - LS-C257913 from LifeSpan Bioscience
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Anti-GPAA1 Antibody (aa46-73, PE) - LS-C257914 from LifeSpan Bioscience
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Anti-GPAA1 Antibody (aa49-77) - LS-C321716 from LifeSpan Bioscience
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Anti-GPAA1 Antibody (C-Terminus) - LS-C80884 from LifeSpan Bioscience
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Anti-GPAA1 Antibody - LS-C155264 from LifeSpan Bioscience
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GPAA1 Antibody - NBP1-62435 from Novus Biologicals
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GPAA1 Antibody - NBP2-16709 from Novus Biologicals
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GPAA1 Antibody - H00008733-A01 from Novus Biologicals
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GPAA1 Polyclonal Antibody - bs-13496R from Bioss
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GPAA1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13496R-A350 from Bioss
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GPAA1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13496R-A488 from Bioss
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GPAA1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13496R-A555 from Bioss
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GPAA1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13496R-A647 from Bioss
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