SS18L1

Gene Symbol SS18L1
Entrez Gene 26039
Alt Symbol CREST, LP2261
Species Human
Gene Type protein-coding
Description synovial sarcoma translocation gene on chromosome 18-like 1
Other Description SS18-like protein 1|SYT homolog 1|calcium-responsive transactivator
Swissprots A8K620 B3KWR8 Q8NE69 E1P5H7 A6NNE3 Q6XYD9 Q5JXJ3 Q6MZV9 Q9BR55 Q9H4K6 O75177 Q6NTH3
Accessions EAW75389 EAW75390 EAW75391 EAW75392 EAW75393 EAW75394 EAW75395 EAW75396 O75177 AB014593 BAA31668 AK125656 BAG54230 AK291485 BAF84174 AK299881 BAG61729 AK308765 AY203931 AAP34454 BC034494 AAH34494 BC068993 AAH68993 BX640848 CAE45918 DC375156 DQ890908 ABM81834 EU176499 ABW03300 XM_005260389 XP_005260446 XM_005260391 XP_005260448 XM_011528764 XP_011527066 XM_011528765 XP_011527067 XM_011528766 XP_011527068 XM_011528767 XP_011527069 NM_001301778 NP_001288707 NM_198935 NP_945173 NR_125980 NR_125981 NM_015558
Function Transcriptional activator which is required for calcium- dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}. Note=Localizes to nuclear bodies. Colocalizes with SGOL1 at kinetochore (By similarity). {ECO:0000250}.
Tissue Specificity Ubiquitous; with lowest levels in spleen.

CREST (A-16) - sc-50909 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CREST (A-16): sc-50909. Western blot analysis of CREST expression in non-transfected: sc-117752 (A) and human CREST transfected: sc-170204 (B) 293T whole cell lysates.

CREST (H-127) - sc-99072 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CREST (H-127): 99072. Western blot analysis of CREST expression in SK-N-MC (A), K-562 (B), Jurkat (C), HeLa (D) and MCF7 (E) nuclear extracts.

CREST (M-15) - sc-50912 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CREST (M-15): sc-50912. Western blot analysis of CREST expression in non-transfected: sc-117752 (A) and human CREST transfected: sc-170204 (B) 293T whole cell lysates.

CREST (S-19) - sc-50914 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CREST (S-19): sc-50914. Western blot analysis of CREST expression in non-transfected: sc-117752 (A) and human CREST transfected: sc-170204 (B) 293T whole cell lysates and SK-N-MC nuclear extract (C).

CREST (Q-15) - sc-50913 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CREST (Q-15): sc-50913. Western blot analysis of CREST expression in HeLa (A), MCF7 (B) and IMR-32 (C) whole cell lysates.

CREST (C-13) - sc-50910 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CREST (C-13): sc-50910. Western blot analysis of CREST expression in non-transfected: sc-117752 (A) and human CREST transfected: sc-170204 (B) 293T whole cell lysates.

Anti-SYT homolog 1 antibody - ab126126 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-SYT homolog 1 antibody (ab126126) at 1/1000 dilution + MCF7 whole cell lysate at 30 µg

Anti-SS18L1 / CREST Antibody (aa271-300, AP) - LS-C241250 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SS18L1 / CREST Antibody (aa271-300, Biotin) - LS-C241251 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SS18L1 / CREST Antibody (aa271-300, APC) - LS-C241252 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SS18L1 / CREST Antibody (aa271-300, FITC) - LS-C241253 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SS18L1 / CREST Antibody (aa271-300, PE) - LS-C241254 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SS18L1 / CREST Antibody (aa271-300, Azide-free, HRP) - LS-C248250 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SS18L1 / CREST Antibody (aa271-300) - LS-C325392 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SS18L1 / CREST Antibody (aa251-300) - LS-C111750 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SS18L1 antibody LS-C111750 Western blot of Jurkat lysate.

Anti-SS18L1 / CREST Antibody - LS-C155446 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: MCF-7 10% SDS PAGE SS18L1 antibody diluted at 1:1000

Anti-SS18L1 / CREST Antibody (aa271-300) - LS-C157095 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SS18L1 Antibody western blot of K562 cell line lysates (35 ug/lane). The SS18L1 antibody detected the SS18L1 protein (arrow).

SS18L1 Antibody - NBP2-20486 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SS18L1 Antibody [NBP2-20486] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 10% SDS PAGE gel, diluted at 1:1000.

SS18L1 Antibody - NBP1-56614 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SS18L1 Antibody [NBP1-56614] - Jurkat cell lysate, concentration 0.2-1 ug/ml.

SS18L1 Antibody - NBP2-20485 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SS18L1 Antibody [NBP2-20485] - Mouse tissue extracts (50 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with CREST antibody [C1C3] diluted at 1:1000.

Anti-SS18L1 antibody produced in rabbit - SAB2700526 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SS18L1: <B>Cat. No. SAB2700526</B>: Immunohistochemical analysis of paraffin-embedded Huh-7 xenograft, using CREST antibody at 1:500 dilution.

ANTI-SS18L1 (CENTER) antibody produced in rabbit - SAB1304653 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SS18L1 (Center): <B>Cat. No. SAB1304653</B>: SS18L1 Antibody (Center) western blot analysis in K562 cell line lysates (35 μg/lane).

Anti-SS18L1 antibody produced in rabbit - SAB2103841 from Sigma-Aldrich

Prices $347.50
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SS18L1, antibody produced in rabbit: <B>Cat. No. SAB2103841</B>: Immunoblotting analysis of SS18L1 in Jurkat cell lysate with SS18L1 anitbody at 1 μg/mL.

SS18L1 antibody - middle region (ARP55923_P050) - ARP55923_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SS18L1-Antibody-Center - AP18184c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
SS18L1 Antibody (Center) (Cat. #AP18184c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SS18L1 antibody detected the SS18L1 protein (arrow).
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