HS3ST1

Gene Symbol HS3ST1
Entrez Gene 9957
Alt Symbol 3OST, 3OST1
Species Human
Gene Type protein-coding
Description heparan sulfate (glucosamine) 3-O-sulfotransferase 1
Other Description 3-OST-1|h3-OST-1|heparan sulfate 3-O-sulfotransferase 1|heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1|heparan sulfate glucosamine 3-O-sulfotransferase 1|heparin-glucosamine 3-O-sulfotransferase
Swissprots B3KUA6 O14792 Q6PEY8
Accessions EAW92699 EAW92700 EAW92701 EAW92702 O14792 AA825270 AF019386 AAB84388 AI478981 AK096823 BAG53368 BC025735 AAH25735 BC057803 AAH57803 BM547276 HQ448559 ADQ33038 XM_011513913 XP_011512215 NM_005114 NP_005105
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site. {ECO:0000269|PubMed:9346953}.
Subcellular Location Golgi apparatus lumen {ECO:0000305}.
Tissue Specificity Highly expressed in the brain and kidney and weakly expressed in the heart, lung and placenta. {ECO:0000269|PubMed:9988767}.
Top Pathways Glycosaminoglycan biosynthesis - heparan sulfate / heparin

Human HS3ST1 full length protein - ab160739 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160739 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human HS3ST1 full length protein - ab171694 from Abcam

Category Protein
Source E. coli
Species Human
15% SDS-PAGE analysis of ab171694 (3µg).

Human HS3ST1 protein fragment - ab160740 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160740 on a 12.5% SDS-PAGE stained with Coomassie Blue.

HS3ST1 Antibody Blocking Peptide - LS-E11657 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Heparan Sulfate 3-O-Sulfotransferase 1/HS3ST1 Partial Recombinant Protein - H00009957-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Heparan Sulfate 3-O-Sulfotransferase 1/HS3ST1 Recombinant Protein - H00009957-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human Heparan Sulfate 3-O-Sulfotransferase 1/HS3ST1 Protein - NBP2-23116 from Novus Biologicals

Category Protein
Prices $269.00
Sizes 50 µg
Source E.coli
Species Human
SDS-Page: HS3ST1 Protein [NBP2-23116]

HS3ST1-Antibody-C-term-Blocking-peptide - BP13378b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human HS3ST1, CF - 5968-ST-020 from R&D Systems

Category Protein
Source Chinese Hamster Ovary cell line, CHO-derived, Arg21-His307, with an N-terminal 6-His tag

Human HS3ST1 (His Tag) protein - orb179748 from Biorbyt

Category Protein
Prices $400.00, $612.00
Sizes 20 μg, 50 μg
Source Baculovirus-Insect Cells
Species Human

HS3ST1 Blocking Peptide - 33R-9139 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

HS3ST1 protein (His tag) - 80R-3026 from Fitzgerald

Category Protein
Prices $275.00
Sizes 50 µg
Source E.coli

HS3ST1 / 3OST (21-307, His-tag) - AR51144PU-N from Acris Antibodies

Category Protein
Prices $790.00
Sizes 250 µg
Source E. coli
Species Human
HS3ST1 / 3OST

HS3ST1 / 3OST (21-307, His-tag) - AR51144PU-S from Acris Antibodies

Category Protein
Prices $340.00
Sizes 50 µg
Source E. coli
Species Human
HS3ST1 / 3OST

HS3ST1 / 3OST - H00009957-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

HS3ST1 / 3OST - H00009957-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

HS3ST1 / 3OST - H00009957-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

HS3ST1 / 3OST - H00009957-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

HS3ST1, 21-307aa, Human, His tag, E.coli - 01-P2320 from ARP American Research Products

Category Protein
Prices $149.00, $369.00, $849.00
Sizes 10 µg, 50 µg, 250 µg
Species Human

HS3ST1 fusion protein - Ag5719 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

HS3ST1 fusion protein - ag5564 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human Heparan Sulfate (glucosamine) 3-O-Sulfotransferase 1, His-tagged - HS3ST1-1970H from Creative Biomart

Category Protein
Source Chinese HamsterOvary cell line, CHO-derived.

Recombinant Human HS3ST1, His-tagged - HS3ST1-13943H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human HS3ST1, His-tagged - HS3ST1-2320H from Creative Biomart

Category Protein
Source E. coli
Species Human

Recombinant Human HS3ST1, His-tagged - HS3ST1-926H from Creative Biomart

Category Protein
Source CHO Cells
Species Human
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