HS3ST1

Gene Symbol HS3ST1
Entrez Gene 9957
Alt Symbol 3OST, 3OST1
Species Human
Gene Type protein-coding
Description heparan sulfate (glucosamine) 3-O-sulfotransferase 1
Other Description 3-OST-1|h3-OST-1|heparan sulfate 3-O-sulfotransferase 1|heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1|heparan sulfate glucosamine 3-O-sulfotransferase 1|heparin-glucosamine 3-O-sulfotransferase
Swissprots B3KUA6 O14792 Q6PEY8
Accessions EAW92699 EAW92700 EAW92701 EAW92702 O14792 AA825270 AF019386 AAB84388 AI478981 AK096823 BAG53368 BC025735 AAH25735 BC057803 AAH57803 BM547276 HQ448559 ADQ33038 XM_011513913 XP_011512215 NM_005114 NP_005105
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site. {ECO:0000269|PubMed:9346953}.
Subcellular Location Golgi apparatus lumen {ECO:0000305}.
Tissue Specificity Highly expressed in the brain and kidney and weakly expressed in the heart, lung and placenta. {ECO:0000269|PubMed:9988767}.
Top Pathways Glycosaminoglycan biosynthesis - heparan sulfate / heparin

HS3ST1 CRISPR/Cas9 KO Plasmid (h) - sc-405358 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HS3ST1 HDR Plasmid (h) - sc-405358-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HS3ST1 Double Nickase Plasmid (h) - sc-405358-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HS3ST1 Double Nickase Plasmid (h2) - sc-405358-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HS3ST1 CRISPR Activation Plasmid (h) - sc-405358-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HS3ST1 CRISPR Activation Plasmid (h2) - sc-405358-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HS3ST1 Lentiviral Activation Particles (h) - sc-405358-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HS3ST1 Lentiviral Activation Particles (h2) - sc-405358-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HS3ST1 siRNA (h) - sc-88999 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HS3ST1 shRNA Plasmid (h) - sc-88999-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HS3ST1 shRNA (h) Lentiviral Particles - sc-88999-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN10306 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10306 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05837 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05837

HS3ST1 siRNA (Human) - CRH6696 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HS3ST1 - MBS8233046 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Hs3st1 (NM_005114.2) - SHH314957 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human HS3ST1(NM_005114.2) - SHH131609 from Creative biogene

Category siRNA
Species Reactivities Human

Human HS3ST1 siRNA - orb267198 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HS3ST1 shRNA Plasmid (Human) - CHH6696 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HS3ST1 miRNA 3'UTR clone - MiUTR1H-04701 from Creative biogene

Species Reactivities Human
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