Gene Symbol | HIST1H1B |
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Entrez Gene | 3009 |
Alt Symbol | H1, H1.5, H1B, H1F5, H1s-3 |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H1b |
Other Description | H1 histone family, member 5|histone 1, H1b|histone H1.5|histone H1a|histone H1b|histone H1s-3 |
Swissprots | Q3MJ42 P16401 Q14529 |
Accessions | AAA35943 AAN06704 CAA29930 CAA58498 EAX03119 P16401 BC069101 AAH69101 BC101581 AAI01582 BC101583 AAI01584 EU446959 ABZ92488 NM_005322 NP_005313 |
Function | Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. Chromosome. Note=According to PubMed:15911621 more commonly found in heterochromatin. According to PubMed:10997781 associates with actively transcribed chromatin and not heterochromatin. |
Tissue Specificity | Ubiquitous. Expressed in the majority of the cell lines tested and in testis. {ECO:0000269|PubMed:9031620}. |
Mouse/Human Phospho-HIST1H1B (Thr17) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1365 from LifeSpan Bioscience
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Mouse/Human HIST1H1B ELISA Kit (Cell-Based ELISA) - LS-F2049 from LifeSpan Bioscience
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Histone H1 (Phospho-Thr17) Colorimetric Cell-Based ELISA Kit - CBP1382 from Assay Biotechnology
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Histone Cluster 1, H1a (HIST1H1A), ELISA Kit - MBS2024854 from MyBioSource
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histone cluster 1, H1b, ELISA Kit - MBS9322257 from MyBioSource
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Human HIST1H1B ELISA Kit - E018747 from Biobool
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