HIST1H1B

Gene Symbol HIST1H1B
Entrez Gene 3009
Alt Symbol H1, H1.5, H1B, H1F5, H1s-3
Species Human
Gene Type protein-coding
Description histone cluster 1, H1b
Other Description H1 histone family, member 5|histone 1, H1b|histone H1.5|histone H1a|histone H1b|histone H1s-3
Swissprots Q3MJ42 P16401 Q14529
Accessions AAA35943 AAN06704 CAA29930 CAA58498 EAX03119 P16401 BC069101 AAH69101 BC101581 AAI01582 BC101583 AAI01584 EU446959 ABZ92488 NM_005322 NP_005313
Function Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). {ECO:0000250}.
Subcellular Location Nucleus. Chromosome. Note=According to PubMed:15911621 more commonly found in heterochromatin. According to PubMed:10997781 associates with actively transcribed chromatin and not heterochromatin.
Tissue Specificity Ubiquitous. Expressed in the majority of the cell lines tested and in testis. {ECO:0000269|PubMed:9031620}.

Human HIST1H1B ORF clone (NM_005322.2) - CDCL117133 from Creative biogene

Species Human

Human HIST1H1B cDNA Clone(NM_005322.2) - CDFH008490 from Creative biogene

Species Human
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