CYP2W1

Gene Symbol CYP2W1
Entrez Gene 54905
Alt Symbol -
Species Human
Gene Type protein-coding
Description cytochrome P450, family 2, subfamily W, polypeptide 1
Other Description CYPIIW1|cytochrome P450 2W1
Swissprots Q8TAV3
Accessions EAW87186 EAW87187 Q8TAV3 AK000366 BAA91114 BC025761 AAH25761 XM_011515440 XP_011513742 XM_011515441 XP_011513743 NM_017781 NP_060251
Function Seems to have broad catalytic activity towards several chemicals, including polycyclic aromatic hydrocarbon dihydrodiols and aromatic amines (PubMed:16551781, PubMed:24278521). Actives also in the metabolism of indoline substrates and is able to activate aflatoxin B1 into cytotoxic products (PubMed:20805301). Furthermore, it seems to be involved in the oxydation of lysophospholipids and fatty acids (PubMed:22591743). {ECO:0000269|PubMed:16551781, ECO:0000269|PubMed:20805301, ECO:0000269|PubMed:22591743, ECO:0000269|PubMed:24278521}.
Subcellular Location Endoplasmic reticulum lumen {ECO:0000269|PubMed:20805301}. Cell membrane {ECO:0000269|PubMed:20805301}. Note=About 8% are expressed on the cell surface. {ECO:0000269|PubMed:20805301}.
Tissue Specificity Very low levels are detected in fetal and adult tissues. Highly expressed in several tumor samples, in particular colon and adrenal tumors. {ECO:0000269|PubMed:16426568}.

CYP2W1 (C-7) - sc-374426 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP2W1 (C-7): sc-374426. Western blot analysis of CYP2W1 expression in non-transfected: sc-117752 (A) and human CYP2W1 transfected: sc-114053 (B) 293T whole cell lysates.

CYP2W1 (F-4) - sc-398523 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP2W1 (F-4): sc-398523. Western blot analysis of CYP2W1 expression in non-transfected 293T: sc-117752 (A), human CYP2W1 transfected 293T: sc-114053 (B) and AMJ2-C8 (C) whole cell lysates.

CYP2W1 (C-17) - sc-48995 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYP2W1 (C-17): sc-48995. Western blot analysis of CYP2W1 expression in non-transfected: sc-117752 (A) and human CYP2W1 transfected: sc-114053 (B) 293T whole cell lysates.

CYP2W1 (G-11) - sc-166331 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP2W1 (G-11): sc-166331. Western blot analysis of CYP2W1 expression in non-transfected: sc-117752 (A) and human CYP2W1 transfected: sc-114053 (B) 293T whole cell lysates.

CYP2W1 (G-12) - sc-48996 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYP2W1 (G-12): sc-48996. Western blot analysis of CYP2W1 expression in non-transfected: sc-117752 (A) and human CYP2W1 transfected: sc-114053 (B) 293T whole cell lysates.

CYP2W1 (M-40) - sc-98921 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

CYP2W1 (H-175) - sc-98920 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CYP2W1 (H-175): sc-98920. Western blot analysis of CYP2W1 expression in non-transfected 293: sc-110760 (A), human CYP2W1 transfected 293: sc-158417 (B) and Hep G2 (C) whole cell lysates.

CYP2W1 (T-17) - sc-48998 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYP2W1 (T-17): sc-48998. Western blot analysis of CYP2W1 expression in non-transfected: sc-117752 (A) and human CYP2W1 transfected: sc-114053 (B) 293T whole cell lysates.

Anti-CYP2W1 antibody - ab113910 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CYP2W1 antibody (ab113910) at 1 µg/ml + Human fetal lung lysate at 10 µg

Anti-CYP2W1 antibody - C-terminal - ab198017 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue labeling CYP2W1 with ab198017 at 1/60 dilution.

Anti-CYP2W1 antibody - N-terminal - ab76666 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CYP2W1 antibody - N-terminal (ab76666) at 1/50 dilution + HepG2 cell lysate at 35 µg

Anti-CYP2W1 Antibody (aa260-309) - LS-C135882 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CYP2W1 antibody LS-C135882 Western blot of Fetal Lung lysate. Antibody concentration 1 ug/ml.

Anti-CYP2W1 Antibody (aa311-360) - LS-C119504 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human liver carcinoma tissue, using Cytochrome P450 2W1 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-CYP2W1 Antibody (N-Terminus) - LS-C96729 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CYP2W1 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

CYP2W1 Antibody - NBP1-83659 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CYP2W1 Polyclonal Antibody - bs-6277R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Cytochrome P450 2W1 antibody produced in rabbit - SAB4502273 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-Cytochrome P450 2W1: <B>Cat. No. SAB4502273</B>: Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using Anti-Cytochrome P450 2W1 antibody. Cells on the left were treated with the Anti-Cytochrome P450 2W1 antibody. Cells on the right (negative control) were treated with both Anti-Cytochrome P450 2W1 antibody and the synthesized immunogen peptide.

ANTI-CYP2W1(N-TERMINAL) antibody produced in rabbit - SAB1307128 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CYP2W1 (N-term): <B>Cat. No. SAB1307128</B>: Formalin-fixed and paraffin-embedded Human lung carcinoma tissue reacted with CYP2W1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this for immunohistochemistry; clinical relevance has not been evaluated.

CYP2W1 antibody - C-terminal region (ARP60779_P050) - ARP60779_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CYP2W1-Antibody-N-term - AP7792a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysates from MCF-7, HepG2 cell line (from left to right), using CYP2W1 Antibody (N-term)(Cat. #AP7792a). AP7792a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.

CYP2W1 Antibody - N-terminal region (OAAB04847) - OAAB04847 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

CYP2W1 antibody, N-term - GTX81289 from GeneTex

Prices $319.00
Sizes 400 μl
Host Rabbit
Clonality Polyclonal
Anti-CYP2W1 antibody, N-term used in IHC (Formalin-fixed paraffin-embedded sections). GTX81289

CYP2W1 Antibody (OAAF02957) - OAAF02957 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CYP2W1 antibody - 70R-16715 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

CYP2W1 antibody - 70R-10177 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
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