Gene Symbol | CYP2W1 |
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Entrez Gene | 54905 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome P450, family 2, subfamily W, polypeptide 1 |
Other Description | CYPIIW1|cytochrome P450 2W1 |
Swissprots | Q8TAV3 |
Accessions | EAW87186 EAW87187 Q8TAV3 AK000366 BAA91114 BC025761 AAH25761 XM_011515440 XP_011513742 XM_011515441 XP_011513743 NM_017781 NP_060251 |
Function | Seems to have broad catalytic activity towards several chemicals, including polycyclic aromatic hydrocarbon dihydrodiols and aromatic amines (PubMed:16551781, PubMed:24278521). Actives also in the metabolism of indoline substrates and is able to activate aflatoxin B1 into cytotoxic products (PubMed:20805301). Furthermore, it seems to be involved in the oxydation of lysophospholipids and fatty acids (PubMed:22591743). {ECO:0000269|PubMed:16551781, ECO:0000269|PubMed:20805301, ECO:0000269|PubMed:22591743, ECO:0000269|PubMed:24278521}. |
Subcellular Location | Endoplasmic reticulum lumen {ECO:0000269|PubMed:20805301}. Cell membrane {ECO:0000269|PubMed:20805301}. Note=About 8% are expressed on the cell surface. {ECO:0000269|PubMed:20805301}. |
Tissue Specificity | Very low levels are detected in fetal and adult tissues. Highly expressed in several tumor samples, in particular colon and adrenal tumors. {ECO:0000269|PubMed:16426568}. |
Human CYP2W1 full length protein - ab162887 from Abcam
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CYP2W1 Antibody Blocking Peptide - LS-E22242 from LifeSpan Bioscience
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CYP2W1 Antibody Blocking Peptide - LS-E9263 from LifeSpan Bioscience
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Recombinant Human CYP2W1 Protein - H00054905-P01 from Novus Biologicals
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CYP2W1-Antibody-N-term-Blocking-Peptide - BP7792a from Abgent, a WuXi AppTec company
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CYP2W1 Blocking Peptide - 33R-7404 from Fitzgerald
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CYP2W1 - H00054905-P01 from Acris Antibodies
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CYP2W1 fusion protein - ag3803 from Proteintech Group
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Recombinant Human Cytochrome P450 2W1(CYP2W1) - CSB-YP823444HU CSB-EP823444HU CSB-BP823444HU CSB-MP823444HU from Cusabio
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CYP2W1 - TP306472 from Acris Antibodies
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Cytochrome P450 2W1 Blocking Peptide - abx061073 from Abbexa
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CYP2W1 Recombinant Protein Antigen - NBP1-83659PEP from Novus Biologicals
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CYP2W1-Antibody-Center-Blocking-Peptide - BP7792c from Abgent, a WuXi AppTec company
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CYP2W1 Peptide, Human - M34GP03967H from Creative Peptides
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Cytochrome P450 2W1 Blocking Peptide - CBP4986 from Cohesion Biosciences
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Cytochrome P450 2W1 (CYP2W1), Recombinant Protein - MBS1354801 from MyBioSource
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