Gene Symbol | CYP2W1 |
---|---|
Entrez Gene | 54905 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome P450, family 2, subfamily W, polypeptide 1 |
Other Description | CYPIIW1|cytochrome P450 2W1 |
Swissprots | Q8TAV3 |
Accessions | EAW87186 EAW87187 Q8TAV3 AK000366 BAA91114 BC025761 AAH25761 XM_011515440 XP_011513742 XM_011515441 XP_011513743 NM_017781 NP_060251 |
Function | Seems to have broad catalytic activity towards several chemicals, including polycyclic aromatic hydrocarbon dihydrodiols and aromatic amines (PubMed:16551781, PubMed:24278521). Actives also in the metabolism of indoline substrates and is able to activate aflatoxin B1 into cytotoxic products (PubMed:20805301). Furthermore, it seems to be involved in the oxydation of lysophospholipids and fatty acids (PubMed:22591743). {ECO:0000269|PubMed:16551781, ECO:0000269|PubMed:20805301, ECO:0000269|PubMed:22591743, ECO:0000269|PubMed:24278521}. |
Subcellular Location | Endoplasmic reticulum lumen {ECO:0000269|PubMed:20805301}. Cell membrane {ECO:0000269|PubMed:20805301}. Note=About 8% are expressed on the cell surface. {ECO:0000269|PubMed:20805301}. |
Tissue Specificity | Very low levels are detected in fetal and adult tissues. Highly expressed in several tumor samples, in particular colon and adrenal tumors. {ECO:0000269|PubMed:16426568}. |
CYP2W1 CRISPR/Cas9 KO Plasmid (h) - sc-404238 from Santa Cruz Biotechnology
|
||||||||
CYP2W1 HDR Plasmid (h) - sc-404238-HDR from Santa Cruz Biotechnology
|
||||||||
CYP2W1 Double Nickase Plasmid (h) - sc-404238-NIC from Santa Cruz Biotechnology
|
||||||||
CYP2W1 Double Nickase Plasmid (h2) - sc-404238-NIC-2 from Santa Cruz Biotechnology
|
||||||||
CYP2W1 CRISPR Activation Plasmid (h) - sc-404238-ACT from Santa Cruz Biotechnology
|
||||||||
CYP2W1 CRISPR Activation Plasmid (h2) - sc-404238-ACT-2 from Santa Cruz Biotechnology
|
||||||||
CYP2W1 Lentiviral Activation Particles (h) - sc-404238-LAC from Santa Cruz Biotechnology
|
||||||||
CYP2W1 Lentiviral Activation Particles (h2) - sc-404238-LAC-2 from Santa Cruz Biotechnology
|
||||||||
CYP2W1 siRNA (h) - sc-60487 from Santa Cruz Biotechnology
|
||||||||
CYP2W1 shRNA Plasmid (h) - sc-60487-SH from Santa Cruz Biotechnology
|
||||||||
CYP2W1 shRNA (h) Lentiviral Particles - sc-60487-V from Santa Cruz Biotechnology
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN2430 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2430 from Sigma-Aldrich
|
||||||||
CYP2W1 siRNA (Human) - CRJ0314 from Cohesion Biosciences
|
||||||||
CYP2W1 RNAi - H00054905-R01 from Novus Biologicals
|
||||||||
CYP2W1 - MBS8236547 from MyBioSource
|
||||||||
shRNA set against Human CYP2W1 (NM_017781.2) - SHH273421 from Creative biogene
|
||||||||
Human CYP2W1 siRNA - orb270815 from Biorbyt
|
||||||||
CYP2W1 shRNA Plasmid (Human) - CHJ0314 from Cohesion Biosciences
|
||||||||
CYP2W1 miRNA 3'UTR clone - MiUTR1H-02629 from Creative biogene
|