Gene Symbol | PLIN1 |
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Entrez Gene | 5346 |
Alt Symbol | FPLD4, PERI, PLIN |
Species | Human |
Gene Type | protein-coding |
Description | perilipin 1 |
Other Description | lipid droplet-associated protein|perilipin-1 |
Swissprots | Q8N5Y6 O60240 |
Accessions | EAX02061 O60240 AB005293 BAA25420 AK310907 BC031084 AAH31084 BQ003487 CA427560 CB266260 CB266707 XM_005254934 XP_005254991 NM_001145311 NP_001138783 NM_002666 NP_002657 |
Function | Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone- sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels. {ECO:0000269|PubMed:23399566}. |
Subcellular Location | Endoplasmic reticulum {ECO:0000269|PubMed:23399566}. Lipid droplet {ECO:0000269|PubMed:23399566}. Note=Lipid droplet surface- associated. |
Tissue Specificity | Adipocytes. {ECO:0000269|PubMed:9521880}. |
Top Pathways | PPAR signaling pathway |
Perilipin (D1D8) XP ® Rabbit mAb - 9349 from Cell Signaling Technology
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Perilipin (K117) Antibody - 3467 from Cell Signaling Technology
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Perilipin (D418) Antibody - 3470 from Cell Signaling Technology
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Perilipin (G-2) - sc-390169 from Santa Cruz Biotechnology
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Perilipin (N-14) - sc-47322 from Santa Cruz Biotechnology
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Perilipin (K-13) - sc-47320 from Santa Cruz Biotechnology
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Perilipin (C-14) - sc-47319 from Santa Cruz Biotechnology
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Perilipin (H-300) - sc-67164 from Santa Cruz Biotechnology
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Anti-Perilipin A antibody - ab50291 from Abcam
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Anti-Perilipin A antibody [EPR3753(2)] - ab172907 from Abcam
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Anti-Perilipin A antibody - Carboxyterminal end - ab61682 from Abcam
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Anti-Perilipin A+B antibody - ab3527 from Abcam
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Anti-Perilipin A+B antibody - ab66514 from Abcam
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Anti-Perilipin-1 antibody - N-terminal - ab192716 from Abcam
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Anti-PLIN1 / Perilipin Antibody (aa502-517) - LS-C26025 from LifeSpan Bioscience
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Anti-PLIN1 / Perilipin Antibody - LS-C48504 from LifeSpan Bioscience
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Anti-PLIN1 / Perilipin Antibody (N-Terminus) - LS-C38145 from LifeSpan Bioscience
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Anti-PLIN1 / Perilipin Antibody (N-Terminus) - LS-C84153 from LifeSpan Bioscience
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Anti-PLIN1 / Perilipin Antibody - LS-C84154 from LifeSpan Bioscience
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Anti-PLIN1 / Perilipin Antibody (aa502-517) - LS-C84217 from LifeSpan Bioscience
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Anti-PLIN1 / Perilipin Antibody (C-Terminus) - LS-C90068 from LifeSpan Bioscience
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Anti-PLIN1 / Perilipin Antibody (C-Terminus, Biotin) - LS-C140916 from LifeSpan Bioscience
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Anti-PLIN1 / Perilipin Antibody (C-Terminus, DY488) - LS-C141344 from LifeSpan Bioscience
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Anti-PLIN1 / Perilipin Antibody (C-Terminus, DY650) - LS-C141343 from LifeSpan Bioscience
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Anti-PLIN1 / Perilipin Antibody (aa81-130) - LS-C31966 from LifeSpan Bioscience
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