Gene Symbol | PLIN1 |
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Entrez Gene | 5346 |
Alt Symbol | FPLD4, PERI, PLIN |
Species | Human |
Gene Type | protein-coding |
Description | perilipin 1 |
Other Description | lipid droplet-associated protein|perilipin-1 |
Swissprots | Q8N5Y6 O60240 |
Accessions | EAX02061 O60240 AB005293 BAA25420 AK310907 BC031084 AAH31084 BQ003487 CA427560 CB266260 CB266707 XM_005254934 XP_005254991 NM_001145311 NP_001138783 NM_002666 NP_002657 |
Function | Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone- sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels. {ECO:0000269|PubMed:23399566}. |
Subcellular Location | Endoplasmic reticulum {ECO:0000269|PubMed:23399566}. Lipid droplet {ECO:0000269|PubMed:23399566}. Note=Lipid droplet surface- associated. |
Tissue Specificity | Adipocytes. {ECO:0000269|PubMed:9521880}. |
Top Pathways | PPAR signaling pathway |
Human Perilipin A protein fragment - ab112340 from Abcam
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Perilipin A+B peptide - ab5010 from Abcam
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Perilipin A peptide - ab5009 from Abcam
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Perilipin A peptide - ab109636 from Abcam
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PLIN1 / Perilipin Antibody Blocking Peptide - LS-E26309 from LifeSpan Bioscience
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PLIN1 / Perilipin Antibody Blocking Peptide - LS-E26310 from LifeSpan Bioscience
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PLIN1 / Perilipin Antibody Blocking Peptide - LS-E15478 from LifeSpan Bioscience
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Perilipin Blocking Peptide - NB110-40760PEP from Novus Biologicals
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Recombinant Human Perilipin Protein - H00005346-Q01 from Novus Biologicals
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Perilipin (C Terminus) blocking peptide - GTX89060-PEP from GeneTex
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Perilipin (internal) blocking peptide - GTX89109-PEP from GeneTex
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Perilipin A Peptide - AC21-1144-P from Abcore
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Perilipin A Peptide - AC21-1145-P from Abcore
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Perilipin-1 - H00005346-Q01-10 from Acris Antibodies
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Perilipin-1 - H00005346-Q01-25 from Acris Antibodies
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Perilipin Peptide - 46-167P from ProSci
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Perilipin Peptide - 46-168P from ProSci
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PLIN fusion protein - ag6124 from Proteintech Group
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Recombinant Perilipin 1 (PLIN1) - RPC745Hu01 from Uscn Life Science Inc.
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Recombinant Perilipin 1 (PLIN1) - RPC745Mu01 from Uscn Life Science Inc.
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Recombinant Perilipin 1 (PLIN1) - RPC745Mu02 from Uscn Life Science Inc.
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Recombinant Perilipin 1 (PLIN1) - RPC745Hu01 from Cloud-clone
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Recombinant Human Perilipin-1(PLIN1) - CSB-YP526447HU CSB-EP526447HU CSB-BP526447HU CSB-MP526447HU from Cusabio
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Perilipin-1 (transcript variant 1) - TP306292 from Acris Antibodies
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Perilipin-1 (PLIN1), Recombinant Protein - MBS1154721 from MyBioSource
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