DSC2

Gene Symbol DSC2
Entrez Gene 1824
Alt Symbol ARVD11, CDHF2, DG2, DGII/III, DSC3
Species Human
Gene Type protein-coding
Description desmocollin 2
Other Description cadherin family member 2|desmocollin-2|desmosomal glycoprotein II/III
Swissprots Q02487
Accessions ABM88172 CAL91822 CAL91823 EAX01250 EAX01251 Q02487 AK290313 BAF83002 AK297029 BAG59557 BC063291 AAH63291 BE350090 BE813598 BU735677 BX648425 CAH56152 CR749226 CAH18082 DC382631 EF017811 ABM88170 EF017812 ABM88171 X56807 CAA40141 XM_005258206 XP_005258263 NM_004949 NP_004940 NM_024422 NP_077740
Function Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
Subcellular Location Cell membrane {ECO:0000269|PubMed:21062920}; Single-pass type I membrane protein {ECO:0000269|PubMed:21062920}. Cell junction, desmosome {ECO:0000269|PubMed:21062920}.
Tissue Specificity Expressed in epithelia, myocardium and lymph nodes.
Top Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC)

DSC2 (D-13) - sc-34311 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DSC2 (D-13): sc-34311. Western blot analysis of DSC2 expression in 293T (A) and NTERA-2 cl.D1 (B) whole cell lysates.

DSC2 (H-50) - sc-66862 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

DSC2 (S-14) - sc-34307 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DSC2 (S-14): sc-34307. Western blot analysis of DSC2 expression in non-transfected 293T: sc-117752 (A) and mouse DSC2 transfected 293T: sc-119847 (B) whole cell lysates.

DSC2 (T-15) - sc-34312 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

DSC2/3 (3G130) - sc-70994 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DSC2/3 (3G130): sc-70994. Western blot analysis of DSC2 and DSC3 expression in HeLa whole cell lysate.

DSC2/3 (7G6) - sc-53485 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DSC2/3 (7G6): sc-53485. Western blot analysis of DSC2 and DSC3 expression in HeLa whole cell lysate.

Anti-Desmocollin 2 + 3 antibody [3G130] - ab69406 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 3G130

Anti-Desmocollin 2 antibody - ab95967 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Desmocollin 2 antibody (ab95967) at 1/500 dilution + A431 whole cell lysate at 30 µg

Anti-Desmocollin 2 antibody - ab72792 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Desmocollin 2 antibody (ab72792) at 1/500 dilutionLane 1 : Desmocollin 2 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-Desmocollin 2 antibody - ab76628 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-Desmocollin 2 antibody (ab76628) at 1 µg/ml + Recombinant tagged human Desmocollin 2 fragment at 0.2 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/5000 dilution

Anti-DSC2 / Desmocollin 2 Antibody (aa480-706) - LS-C186031 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded OVCAR3 xenograft using Desmocollin 2 antibody at 1:500 dilution.

Anti-DSC2 / Desmocollin 2 Antibody - LS-C84140 from LifeSpan Bioscience

Prices $560.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DSC2 / Desmocollin 2 Antibody - LS-C86058 from LifeSpan Bioscience

Prices $560.00
Sizes 100 µl
Host Guinea Pig
Clonality Polyclonal

Anti-DSC2 / Desmocollin 2 Antibody - LS-C22806 from LifeSpan Bioscience

Prices $620.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DSC2 / Desmocollin 2 Antibody - LS-C307905 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-DSC2 / Desmocollin 2 Antibody - LS-C310173 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DSC2 / Desmocollin 2 Antibody (aa136-694) - LS-C182831 from LifeSpan Bioscience

Prices $620.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-DSC2 / Desmocollin 2 Antibody (clone 1F2) - LS-C197081 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F2
DSC2 monoclonal antibody (M14), clone 1F2. Western Blot analysis of DSC2 expression in human spleen.

Desmocollin-2 Antibody - AF4688 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal

Desmocollin-2 Antibody - NBP1-32961 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Desmocollin-2 Antibody [NBP1-32961] - Sample (30 ug of whole cell lysate) A: A431 7. 5% SDS PAGE, antibody diluted at 1:500.

Desmocollin-2 Antibody - 22470002 from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ELISA: Desmocollin-2 Antibody [22470002]

Desmocollin-2 Antibody - NBP1-85710 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Desmocollin-2 Antibody [NBP1-85710] - Staining of human esophagus shows strong membranous positivity in squamous epithelial cells.

Desmocollin-2 Antibody - NBP1-85711 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: Desmocollin-2 Antibody [NBP1-85711] - Immunohistochemical staining of human esophagus shows strong membranous positivity in squamous epithelial cells.

Desmocollin-2 Antibody - H00001824-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Desmocollin-2 Antibody [H00001824-D01P] - Analysis of DSC2 expression in human stomach.

Desmocollin-2 Antibody - H00001824-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Desmocollin 2 Antibody [H00001824-B01] - analysis of DSC2 expression in transfected 293T cell line by DSC2 MaxPab polyclonal antibody (B01). Lane 1: DSC2 transfected lysate (93.80 KDa). Lane 2: Non-transfected lysate.
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