DSC2

Gene Symbol	DSC2
Entrez Gene	1824
Alt Symbol	ARVD11, CDHF2, DG2, DGII/III, DSC3
Species	Human
Gene Type	protein-coding
Description	desmocollin 2
Other Description	cadherin family member 2|desmocollin-2|desmosomal glycoprotein II/III
Swissprots	Q02487
Accessions	ABM88172 CAL91822 CAL91823 EAX01250 EAX01251 Q02487 AK290313 BAF83002 AK297029 BAG59557 BC063291 AAH63291 BE350090 BE813598 BU735677 BX648425 CAH56152 CR749226 CAH18082 DC382631 EF017811 ABM88170 EF017812 ABM88171 X56807 CAA40141 XM_005258206 XP_005258263 NM_004949 NP_004940 NM_024422 NP_077740
Function	Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:21062920}; Single-pass type I membrane protein {ECO:0000269|PubMed:21062920}. Cell junction, desmosome {ECO:0000269|PubMed:21062920}.
Tissue Specificity	Expressed in epithelia, myocardium and lymph nodes.
Top Pathways	Arrhythmogenic right ventricular cardiomyopathy (ARVC)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Desmocollin 2 full length protein - ab158317 from Abcam Category Protein Source Wheat germ Species Human

Human Desmocollin 2 protein fragment - ab158318 from Abcam Category Protein Source Wheat germ Species Human

Human Desmocollin 2 protein fragment - ab158319 from Abcam Category Protein Source Wheat germ Species Human

Human Desmocollin 2 protein fragment - ab190408 from Abcam Category Protein Source E. coli Species Human

Recombinant Human Desmocollin-2, CF - 4688-DC-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Arg136-Arg684, with a C-terminal 6-His tag

Desmocollin-2 - H00001824-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Desmocollin-2 - H00001824-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Desmocollin-2 - H00001824-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Desmocollin-2 - H00001824-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Desmocollin-2 - H00001824-Q02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

Desmocollin-2 - H00001824-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Desmocollin-2 - H00001824-Q02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DSC2 fusion protein - ag4956 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

DSC2 fusion protein - Ag5450 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human DSC2, His tagged - DSC2-3856H from Creative Biomart Category Protein Source Human Cells Species Human

DSC2 - PN201490 from Elabscience Category Protein Prices $225.00, $475.00 Sizes 10 μg, 50 μg Source Human Cells Species Human

Recombinant Desmocollin 2 (DSC2) - RPG436Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Human DSC2 / Desmocollin-2 Protein (His Tag) - 10809-H08H-50 from Sino Biological Category Protein Source Human Cells Species Human

Recombinant Desmocollin 2 (DSC2) - RPG436Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Desmocollin-2 Protein, CF - 4688-DC from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Mouse myeloma cell line, NS0-derived Arg136-Arg684, with a C-terminal 6-His tag Species Human

Desmocollin 2 Protein (Recombinant) - abx168158 from Abbexa Category Protein Source Human Species Human

Desmocollin-2 (transcript variant Dsc2a) - TP309218 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Desmocollin-2 (transcript variant Dsc2b) - TP322207 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human DSC2 / Desmocollin-2 Protein (His tag) - PKSH031417 from Elabscience Category Protein Source Human Cell Species Human

Recombinant Desmocollin 2 (DSC2) - RPU52298 from Biomatik Category Protein Prices $185.00, $378.00, $578.00, $688.80 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

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