DSC2

Gene Symbol	DSC2
Entrez Gene	1824
Alt Symbol	ARVD11, CDHF2, DG2, DGII/III, DSC3
Species	Human
Gene Type	protein-coding
Description	desmocollin 2
Other Description	cadherin family member 2|desmocollin-2|desmosomal glycoprotein II/III
Swissprots	Q02487
Accessions	ABM88172 CAL91822 CAL91823 EAX01250 EAX01251 Q02487 AK290313 BAF83002 AK297029 BAG59557 BC063291 AAH63291 BE350090 BE813598 BU735677 BX648425 CAH56152 CR749226 CAH18082 DC382631 EF017811 ABM88170 EF017812 ABM88171 X56807 CAA40141 XM_005258206 XP_005258263 NM_004949 NP_004940 NM_024422 NP_077740
Function	Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:21062920}; Single-pass type I membrane protein {ECO:0000269|PubMed:21062920}. Cell junction, desmosome {ECO:0000269|PubMed:21062920}.
Tissue Specificity	Expressed in epithelia, myocardium and lymph nodes.
Top Pathways	Arrhythmogenic right ventricular cardiomyopathy (ARVC)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DSC2 ORF Clone(NM_024422.3) - CDCL161546 from Creative Biomart Species Human Accession NM_024422.3

Human DSC2 ORF clone(NM_004949.3) - CDCH385967 from Creative Biomart Species Human Accession NM_004949.3

Human DSC2 Gene ORF cDNA clone in cloning vector - HG10809-M from Sino Biological Species Human

Human DSC2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10809-ACR from Sino Biological Species Human

Human DSC2 Gene ORF cDNA clone expression plasmid - HG10809-UT from Sino Biological Species Human

Human DSC2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10809-ACG from Sino Biological Species Human

Human DSC2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10809-NF from Sino Biological Species Human

Human DSC2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10809-NM from Sino Biological Species Human

Human DSC2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10809-CF from Sino Biological Species Human

Human DSC2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10809-CY from Sino Biological Species Human

Human DSC2 Gene ORF cDNA clone expression plasmid, N-His tag - HG10809-NH from Sino Biological Species Human

Human DSC2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10809-CM from Sino Biological Species Human

Human DSC2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10809-NY from Sino Biological Species Human

Human DSC2 Gene ORF cDNA clone expression plasmid, C-His tag - HG10809-CH from Sino Biological Species Human

Human Desmocollin-2 ORF clone(NM_024422.3) - CDCL183913 from Creative biogene Species Human

Human DSC2 ORF clone (NM_004949.3) - CDCR057408 from Creative biogene Species Human

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